Archivio Istituzionale della RicercaARSICCIO, ANDREA
ARSICCIO, ANDREA
Dipartimento Scienza Applicata e Tecnologia
038111
Understanding glucagon aggregation: in silico insights and experimental validation
2024 Pisano, Roberto; Arsiccio, Andrea; Collins, Valerie; King, Patrick; Macis, Marco; Cabri, Walter; Ricci, Antonio
Mechanistic Investigation of tert-Butanol’s Impact on Biopharmaceutical Formulations: When Experiments Meet Molecular Dynamics
2023 Rospiccio, Marcello; Casucci, Paola; Arsiccio, Andrea; Udrescu, Claudia; Pisano, Roberto
Thermodynamic modeling and experimental data reveal that sugars stabilize proteins according to an excluded volume mechanism
2023 Arsiccio, Andrea; Sarter, Tim; Polidori, Ilaria; Winter, Gerhard; Pisano, Roberto; Shea, Joan-Emma
A new transfer free energy based implicit solvation model for the description of disordered and folded proteins
2022 Arsiccio, Andrea; Pisano, Roberto; Shea, Joan-Emma
A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII
2022 Arsiccio, Andrea; Metcalfe, Clive; Pisano, Roberto; Raut, Sanj; Coxon, Carmen
Effect of diffusion kinetics on the ice nucleation temperature distribution
2022 Stratta, Lorenzo; Arsiccio, Andrea; Pisano, Roberto
Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins
2021 Arsiccio, Andrea; Rospiccio, Marcello; Shea, Joan-Emma; Pisano, Roberto
Surface treatment of glass vials for lyophilization: Implications for vacuum-induced surface freezing
2021 Regis, F.; Arsiccio, A.; Bourles, E.; Scutella, B.; Pisano, R.
The role of cyclodextrins against interface-induced denaturation in pharmaceutical formulations: a molecular dynamics approach
2021 Rospiccio, M.; Arsiccio, A.; Winter, G.; Pisano, R.
A model-based approach for the rational design of the freeze-thawing of a protein-based formulation
2020 Arsiccio, A.; Marenco, L.; Pisano, R.
ADD force field for sugars and polyols: predicting the additivity of protein-osmolyte interaction
2020 Arsiccio, A.; Ganguly, P.; La Cortiglia, L.; Shea, J. -E.; Pisano, R.
Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach
2020 Arsiccio, A.; Giorsello, P.; Marenco, L.; Pisano, R.
Heightened cold-denaturation of proteins at the ice-water interface
2020 Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.
Impact of controlled vacuum induced surface freezing on the freeze drying of human plasma
2020 Arsiccio, A.; Matejtschuk, P.; Ezeajughi, E.; Riches-Duit, A.; Bullen, A.; Malik, K.; Raut, S.; Pisano, R.
The ice-water interface and protein stability: a review
2020 Arsiccio, A.; Pisano, R.
Vacuum-induced surface freezing for the freeze-drying of the Human Growth Hormone: how does nucleation control affect protein stability?
2020 Oddone, I.; Arsiccio, A.; Duru, C.; Malik, K.; Ferguson, J.; Pisano, R.; Matejtschuk, P.
Achieving continuous manufacturing in lyophilization: technologies and approaches
2019 Pisano, R.; Arsiccio, A.; Capozzi, L. C.; Trout, B. L.
Designing the optimal formulation for biopharmaceuticals: a new approach combining molecular dynamics and experiments
2019 Arsiccio, Andrea; Paladini, Andrea; Pattarino, Franco; Pisano, Roberto
Measuring and predicting pore size distribution of freeze-dried solutions
2019 Arsiccio, A.; Sparavigna, A. C.; Pisano, R.; Barresi, A. A.
Tuning, measurement and prediction of the impact of freezing on product morphology: A step toward improved design of freeze-drying cycles
2019 Pisano, R.; Arsiccio, A.; Nakagawa, K.; Barresi, A. A.
| Citazione | Data di pubblicazione | Autori | File |
|---|---|---|---|
| Understanding glucagon aggregation: in silico insights and experimental validation / Pisano, R., Arsiccio, A., Collins, V., King, P., Macis, M., Cabri, W., Ricci, A.. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8384. - 21:8(2024), pp. 3815-3823. [10.1021/acs.molpharmaceut.4c00038] | 1-gen-2024 | Pisano, RobertoArsiccio, Andrea + | a-2024_MP_21_3815-3823.pdf; a-2024_MP_21_3815-3823_(authors-version).pdf |
| Mechanistic Investigation of tert-Butanol’s Impact on Biopharmaceutical Formulations: When Experiments Meet Molecular Dynamics / Rospiccio, M., Casucci, P., Arsiccio, A., Udrescu, C., Pisano, R.. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8392. - ELETTRONICO. - 20:8(2023), pp. 3975-3986. [10.1021/acs.molpharmaceut.3c00125] | 1-gen-2023 | Marcello RospiccioPaola CasucciAndrea ArsiccioClaudia UdrescuRoberto Pisano | acs.molpharmaceut.3c00125.pdf; mp3c00125_si_001.pdf |
| Thermodynamic modeling and experimental data reveal that sugars stabilize proteins according to an excluded volume mechanism / Arsiccio, A., Sarter, T., Polidori, I., Winter, G., Pisano, R., Shea, J.. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 1520-5126. - 145:30(2023), pp. 16678-16690. [10.1021/jacs.3c04293] | 1-gen-2023 | Andrea ArsiccioRoberto Pisano + | a-2023_JACS_145(30)_16678-16690.pdf; a-2023_JACS_145(30)_16678-16690_(pre-print).pdf |
| A new transfer free energy based implicit solvation model for the description of disordered and folded proteins / Arsiccio, A., Pisano, R., Shea, J.. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - 126:33(2022), pp. 6180-6190. [10.1021/acs.jpcb.2c03980] | 1-gen-2022 | Arsiccio, AndreaPisano, Roberto + | a-2022_JPCB_126_6180-6190.pdf |
| A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII / Arsiccio, A., Metcalfe, C., Pisano, R., Raut, S., Coxon, C.. - In: PLOS ONE. - ISSN 1932-6203. - 17:2(2022), pp. 1-24. [10.1371/journal.pone.0262409] | 1-gen-2022 | Arsiccio, AndreaPisano, Roberto + | a-2022_PO_17(2)_e0262409.pdf |
| Effect of diffusion kinetics on the ice nucleation temperature distribution / Stratta, L., Arsiccio, A., Pisano, R.. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 12:(2022), pp. 1-10. [10.1038/s41598-022-20797-1] | 1-gen-2022 | Stratta, LorenzoArsiccio, AndreaPisano, Roberto | a-2022_SR_12_16334.pdf |
| Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins / Arsiccio, A., Rospiccio, M., Shea, J., Pisano, R.. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 125:27(2021), pp. 7397-7405. [10.1021/acs.jpcb.1c04033] | 1-gen-2021 | Arsiccio, AndreaRospiccio, MarcelloPisano, Roberto + | acs.jpcb.1c04033.pdf |
| Surface treatment of glass vials for lyophilization: Implications for vacuum-induced surface freezing / Regis, F., Arsiccio, A., Bourles, E., Scutella, B., Pisano, R.. - In: PHARMACEUTICS. - ISSN 1999-4923. - ELETTRONICO. - 13:11(2021), p. 1766. [10.3390/pharmaceutics13111766] | 1-gen-2021 | Regis F.Arsiccio A.Pisano R. + | pharmaceutics-13-01766.pdf |
| The role of cyclodextrins against interface-induced denaturation in pharmaceutical formulations: a molecular dynamics approach / Rospiccio, M., Arsiccio, A., Winter, G., Pisano, R.. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8384. - STAMPA. - 18:6(2021), pp. 2322-2333. [10.1021/acs.molpharmaceut.1c00135] | 1-gen-2021 | Rospiccio M.Arsiccio A.Pisano R. + | a-2021_MP_18(1)_2322-2333.pdf; a-2021_MP_18(1)_2322-2333_(AAM).pdf |
| A model-based approach for the rational design of the freeze-thawing of a protein-based formulation / Arsiccio, A., Marenco, L., Pisano, R.. - In: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. - ISSN 1083-7450. - STAMPA. - 25:7(2020), pp. 823-831. [10.1080/10837450.2020.1743719] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_PDT_25(7)_823-831_(post-print).pdf; a-2020_PDT_25(7)_823-831.pdf |
| ADD force field for sugars and polyols: predicting the additivity of protein-osmolyte interaction / Arsiccio, A., Ganguly, P., La Cortiglia, L., Shea, J.-E., Pisano, R.. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 124:36(2020), pp. 7779-7790. [10.1021/acs.jpcb.0c05345] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_JPCB_124(36)_7779-7790_(post-print).pdf; a-2020_JPCB_124(36)_7779-7790.pdf |
| Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach / Arsiccio, A., Giorsello, P., Marenco, L., Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 464-475. [10.1016/j.xphs.2019.10.022] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_109(1)_464-475.pdf; a-2020_109(1)_464-475_(post-print).pdf |
| Heightened cold-denaturation of proteins at the ice-water interface / Arsiccio, A., Mccarty, J., Pisano, R., Shea, J.-E.. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - 142:12(2020), pp. 5722-5730. [10.1021/jacs.9b13454] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_JACS_142(12)_5722-5730.pdf |
| Impact of controlled vacuum induced surface freezing on the freeze drying of human plasma / Arsiccio, A., Matejtschuk, P., Ezeajughi, E., Riches-Duit, A., Bullen, A., Malik, K., Raut, S., Pisano, R.. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - STAMPA. - 582:(2020), p. 119290. [10.1016/j.ijpharm.2020.119290] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_IJP_582_119290_(post-print).pdf; a-2020_IJP_582_119290.pdf |
| The ice-water interface and protein stability: a review / Arsiccio, A., Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:7(2020), pp. 2116-2130. [10.1016/j.xphs.2020.03.022] | 1-gen-2020 | Arsiccio A.Pisano R. | a-2020_JPS_109(7)_2116-2130_(post-print).pdf; a-2020_JPS_109(7)_2116-2130.pdf |
| Vacuum-induced surface freezing for the freeze-drying of the Human Growth Hormone: how does nucleation control affect protein stability? / Oddone, I., Arsiccio, A., Duru, C., Malik, K., Ferguson, J., Pisano, R., Matejtschuk, P.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 254-263. [10.1016/j.xphs.2019.04.014] | 1-gen-2020 | Oddone I.Arsiccio A.Pisano R. + | a-2020_JPS_109(1)_254-263.pdf |
| Achieving continuous manufacturing in lyophilization: technologies and approaches / Pisano, R., Arsiccio, A., Capozzi, L.C., Trout, B.L.. - In: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. - ISSN 0939-6411. - STAMPA. - 142:(2019), pp. 265-279. [10.1016/j.ejpb.2019.06.027] | 1-gen-2019 | Pisano R.Arsiccio A.Capozzi L. C. + | a-2019_EJPB_142(1)_265-279.pdf |
| Designing the optimal formulation for biopharmaceuticals: a new approach combining molecular dynamics and experiments / Arsiccio, A., Paladini, A., Pattarino, F., Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 108:1(2019), pp. 431-438. [10.1016/j.xphs.2018.09.002] | 1-gen-2019 | Arsiccio, AndreaPaladini, AndreaPisano, Roberto + | a-2019_JPS_108(1)_431-438.pdf |
| Measuring and predicting pore size distribution of freeze-dried solutions / Arsiccio, A., Sparavigna, A.C., Pisano, R., Barresi, A.A.. - In: DRYING TECHNOLOGY. - ISSN 0737-3937. - STAMPA. - 37:4(2019), pp. 435-447. [10.1080/07373937.2018.1430042] | 1-gen-2019 | Arsiccio, A.Sparavigna, A. C.Pisano, R.Barresi, A. A. | 2019_DT_34_Measuring and predicting pore size distribution of freeze dried solutions.pdf; 2019_DT_37(4)_435_postprint.pdf |
| Tuning, measurement and prediction of the impact of freezing on product morphology: A step toward improved design of freeze-drying cycles / Pisano, R., Arsiccio, A., Nakagawa, K., Barresi, A.A.. - In: DRYING TECHNOLOGY. - ISSN 0737-3937. - STAMPA. - 37:5(2019), pp. 579-599. [10.1080/07373937.2018.1528451] | 1-gen-2019 | Pisano R.Arsiccio A.Barresi A. A. + | a-2019_DT_37(5)_579-599.pdf; 2019_DT_37_special-issue-tsotsas_postprint.pdf |