ARSICCIO, ANDREA

ARSICCIO, ANDREA  

038111  

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Mechanistic Investigation of tert-Butanol’s Impact on Biopharmaceutical Formulations: When Experiments Meet Molecular Dynamics / Rospiccio, Marcello; Casucci, Paola; Arsiccio, Andrea; Udrescu, Claudia; Pisano, Roberto. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8392. - ELETTRONICO. - 20:8(2023), pp. 3975-3986. [10.1021/acs.molpharmaceut.3c00125] 1-gen-2023 Marcello RospiccioPaola CasucciAndrea ArsiccioClaudia UdrescuRoberto Pisano acs.molpharmaceut.3c00125.pdfmp3c00125_si_001.pdf
Thermodynamic modeling and experimental data reveal that sugars stabilize proteins according to an excluded volume mechanism / Arsiccio, Andrea; Sarter, Tim; Polidori, Ilaria; Winter, Gerhard; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 1520-5126. - 145:30(2023), pp. 16678-16690. [10.1021/jacs.3c04293] 1-gen-2023 Andrea ArsiccioRoberto Pisano + a-2023_JACS_145(30)_16678-16690.pdfa-2023_JACS_145(30)_16678-16690_(pre-print).pdf
A new transfer free energy based implicit solvation model for the description of disordered and folded proteins / Arsiccio, Andrea; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - 126:33(2022), pp. 6180-6190. [10.1021/acs.jpcb.2c03980] 1-gen-2022 Arsiccio, AndreaPisano, Roberto + a-2022_JPCB_126_6180-6190.pdf
A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII / Arsiccio, Andrea; Metcalfe, Clive; Pisano, Roberto; Raut, Sanj; Coxon, Carmen. - In: PLOS ONE. - ISSN 1932-6203. - 17:2(2022), pp. 1-24. [10.1371/journal.pone.0262409] 1-gen-2022 Arsiccio, AndreaPisano, Roberto + a-2022_PO_17(2)_e0262409.pdf
Effect of diffusion kinetics on the ice nucleation temperature distribution / Stratta, Lorenzo; Arsiccio, Andrea; Pisano, Roberto. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 12:(2022), pp. 1-10. [10.1038/s41598-022-20797-1] 1-gen-2022 Stratta, LorenzoArsiccio, AndreaPisano, Roberto a-2022_SR_12_16334.pdf
Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins / Arsiccio, Andrea; Rospiccio, Marcello; Shea, Joan-Emma; Pisano, Roberto. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 125:27(2021), pp. 7397-7405. [10.1021/acs.jpcb.1c04033] 1-gen-2021 Arsiccio, AndreaRospiccio, MarcelloPisano, Roberto + acs.jpcb.1c04033.pdf
Surface treatment of glass vials for lyophilization: Implications for vacuum-induced surface freezing / Regis, F.; Arsiccio, A.; Bourles, E.; Scutella, B.; Pisano, R.. - In: PHARMACEUTICS. - ISSN 1999-4923. - ELETTRONICO. - 13:11(2021), p. 1766. [10.3390/pharmaceutics13111766] 1-gen-2021 Regis F.Arsiccio A.Pisano R. + pharmaceutics-13-01766.pdf
The role of cyclodextrins against interface-induced denaturation in pharmaceutical formulations: a molecular dynamics approach / Rospiccio, M.; Arsiccio, A.; Winter, G.; Pisano, R.. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8384. - STAMPA. - 18:6(2021), pp. 2322-2333. [10.1021/acs.molpharmaceut.1c00135] 1-gen-2021 Rospiccio M.Arsiccio A.Pisano R. + a-2021_MP_18(1)_2322-2333.pdfa-2021_MP_18(1)_2322-2333_(AAM).pdf
A model-based approach for the rational design of the freeze-thawing of a protein-based formulation / Arsiccio, A.; Marenco, L.; Pisano, R.. - In: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. - ISSN 1083-7450. - STAMPA. - 25:7(2020), pp. 823-831. [10.1080/10837450.2020.1743719] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_PDT_25(7)_823-831_(post-print).pdfa-2020_PDT_25(7)_823-831.pdf
ADD force field for sugars and polyols: predicting the additivity of protein-osmolyte interaction / Arsiccio, A.; Ganguly, P.; La Cortiglia, L.; Shea, J. -E.; Pisano, R.. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 124:36(2020), pp. 7779-7790. [10.1021/acs.jpcb.0c05345] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_JPCB_124(36)_7779-7790_(post-print).pdfa-2020_JPCB_124(36)_7779-7790.pdf
Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach / Arsiccio, A.; Giorsello, P.; Marenco, L.; Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 464-475. [10.1016/j.xphs.2019.10.022] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_109(1)_464-475.pdfa-2020_109(1)_464-475_(post-print).pdf
Heightened cold-denaturation of proteins at the ice-water interface / Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - 142:12(2020), pp. 5722-5730. [10.1021/jacs.9b13454] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_JACS_142(12)_5722-5730.pdf
Impact of controlled vacuum induced surface freezing on the freeze drying of human plasma / Arsiccio, A.; Matejtschuk, P.; Ezeajughi, E.; Riches-Duit, A.; Bullen, A.; Malik, K.; Raut, S.; Pisano, R.. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - STAMPA. - 582:(2020), p. 119290. [10.1016/j.ijpharm.2020.119290] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_IJP_582_119290_(post-print).pdfa-2020_IJP_582_119290.pdf
The ice-water interface and protein stability: a review / Arsiccio, A.; Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:7(2020), pp. 2116-2130. [10.1016/j.xphs.2020.03.022] 1-gen-2020 Arsiccio A.Pisano R. a-2020_JPS_109(7)_2116-2130_(post-print).pdfa-2020_JPS_109(7)_2116-2130.pdf
Vacuum-induced surface freezing for the freeze-drying of the Human Growth Hormone: how does nucleation control affect protein stability? / Oddone, I.; Arsiccio, A.; Duru, C.; Malik, K.; Ferguson, J.; Pisano, R.; Matejtschuk, P.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 254-263. [10.1016/j.xphs.2019.04.014] 1-gen-2020 Oddone I.Arsiccio A.Pisano R. + a-2020_JPS_109(1)_254-263.pdf
Achieving continuous manufacturing in lyophilization: technologies and approaches / Pisano, R.; Arsiccio, A.; Capozzi, L. C.; Trout, B. L.. - In: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. - ISSN 0939-6411. - STAMPA. - 142:(2019), pp. 265-279. [10.1016/j.ejpb.2019.06.027] 1-gen-2019 Pisano R.Arsiccio A.Capozzi L. C. + a-2019_EJPB_142(1)_265-279.pdf
Designing the optimal formulation for biopharmaceuticals: a new approach combining molecular dynamics and experiments / Arsiccio, Andrea; Paladini, Andrea; Pattarino, Franco; Pisano, Roberto. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 108:1(2019), pp. 431-438. [10.1016/j.xphs.2018.09.002] 1-gen-2019 Arsiccio, AndreaPaladini, AndreaPisano, Roberto + a-2019_JPS_108(1)_431-438.pdf
Measuring and predicting pore size distribution of freeze-dried solutions / Arsiccio, A.; Sparavigna, A. C.; Pisano, R.; Barresi, A. A.. - In: DRYING TECHNOLOGY. - ISSN 0737-3937. - STAMPA. - 37:4(2019), pp. 435-447. [10.1080/07373937.2018.1430042] 1-gen-2019 Arsiccio, A.Sparavigna, A. C.Pisano, R.Barresi, A. A. 2019_DT_34_Measuring and predicting pore size distribution of freeze dried solutions.pdf2019_DT_37(4)_435_postprint.pdf
Tuning, measurement and prediction of the impact of freezing on product morphology: A step toward improved design of freeze-drying cycles / Pisano, R.; Arsiccio, A.; Nakagawa, K.; Barresi, A. A.. - In: DRYING TECHNOLOGY. - ISSN 0737-3937. - STAMPA. - 37:5(2019), pp. 579-599. [10.1080/07373937.2018.1528451] 1-gen-2019 Pisano R.Arsiccio A.Barresi A. A. + a-2019_DT_37(5)_579-599.pdf2019_DT_37_special-issue-tsotsas_postprint.pdf
Application of the Quality by Design approach to the freezing step of freeze-drying: building the design space / Arsiccio, Andrea; Pisano, Roberto. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 107:6(2018), pp. 1586-1596. [10.1016/j.xphs.2018.02.003] 1-gen-2018 Arsiccio, AndreaPisano, Roberto a-2018_JPS_107(6)_1586-1596.pdf