ARSICCIO, ANDREA

ARSICCIO, ANDREA  

038111  

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Citazione Data di pubblicazione Autori File
Insights from molecular dynamics simulations for the design of lyophilized protein formulations / Arsiccio, Andrea; Pisano, Roberto - In: From Current to Future Trends in Pharmaceutical Technology / Pippa N., Demetzos C., Chountoulesi M.. - STAMPA. - Cambridge, Massachusetts : Academic Press, 2024. - ISBN 9780323911115. - pp. 145-175 [10.1016/B978-0-323-91111-5.00004-4] 1-gen-2024 Arsiccio, AndreaPisano, Roberto b-2024_Academic-press_formulation_145-175.pdf
Understanding glucagon aggregation: in silico insights and experimental validation / Pisano, Roberto; Arsiccio, Andrea; Collins, Valerie; King, Patrick; Macis, Marco; Cabri, Walter; Ricci, Antonio. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8384. - 21:8(2024), pp. 3815-3823. [10.1021/acs.molpharmaceut.4c00038] 1-gen-2024 Pisano, RobertoArsiccio, Andrea + a-2024_MP_21_3815-3823.pdfa-2024_MP_21_3815-3823_(authors-version).pdf
Mechanistic Investigation of tert-Butanol’s Impact on Biopharmaceutical Formulations: When Experiments Meet Molecular Dynamics / Rospiccio, Marcello; Casucci, Paola; Arsiccio, Andrea; Udrescu, Claudia; Pisano, Roberto. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8392. - ELETTRONICO. - 20:8(2023), pp. 3975-3986. [10.1021/acs.molpharmaceut.3c00125] 1-gen-2023 Marcello RospiccioPaola CasucciAndrea ArsiccioClaudia UdrescuRoberto Pisano acs.molpharmaceut.3c00125.pdfmp3c00125_si_001.pdf
Thermodynamic modeling and experimental data reveal that sugars stabilize proteins according to an excluded volume mechanism / Arsiccio, Andrea; Sarter, Tim; Polidori, Ilaria; Winter, Gerhard; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 1520-5126. - 145:30(2023), pp. 16678-16690. [10.1021/jacs.3c04293] 1-gen-2023 Andrea ArsiccioRoberto Pisano + a-2023_JACS_145(30)_16678-16690.pdfa-2023_JACS_145(30)_16678-16690_(pre-print).pdf
A new transfer free energy based implicit solvation model for the description of disordered and folded proteins / Arsiccio, Andrea; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - 126:33(2022), pp. 6180-6190. [10.1021/acs.jpcb.2c03980] 1-gen-2022 Arsiccio, AndreaPisano, Roberto + a-2022_JPCB_126_6180-6190.pdf
A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII / Arsiccio, Andrea; Metcalfe, Clive; Pisano, Roberto; Raut, Sanj; Coxon, Carmen. - In: PLOS ONE. - ISSN 1932-6203. - 17:2(2022), pp. 1-24. [10.1371/journal.pone.0262409] 1-gen-2022 Arsiccio, AndreaPisano, Roberto + a-2022_PO_17(2)_e0262409.pdf
Effect of diffusion kinetics on the ice nucleation temperature distribution / Stratta, Lorenzo; Arsiccio, Andrea; Pisano, Roberto. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 12:(2022), pp. 1-10. [10.1038/s41598-022-20797-1] 1-gen-2022 Stratta, LorenzoArsiccio, AndreaPisano, Roberto a-2022_SR_12_16334.pdf
Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins / Arsiccio, Andrea; Rospiccio, Marcello; Shea, Joan-Emma; Pisano, Roberto. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 125:27(2021), pp. 7397-7405. [10.1021/acs.jpcb.1c04033] 1-gen-2021 Arsiccio, AndreaRospiccio, MarcelloPisano, Roberto + acs.jpcb.1c04033.pdf
Surface treatment of glass vials for lyophilization: Implications for vacuum-induced surface freezing / Regis, F.; Arsiccio, A.; Bourles, E.; Scutella, B.; Pisano, R.. - In: PHARMACEUTICS. - ISSN 1999-4923. - ELETTRONICO. - 13:11(2021), p. 1766. [10.3390/pharmaceutics13111766] 1-gen-2021 Regis F.Arsiccio A.Pisano R. + pharmaceutics-13-01766.pdf
The role of cyclodextrins against interface-induced denaturation in pharmaceutical formulations: a molecular dynamics approach / Rospiccio, M.; Arsiccio, A.; Winter, G.; Pisano, R.. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8384. - STAMPA. - 18:6(2021), pp. 2322-2333. [10.1021/acs.molpharmaceut.1c00135] 1-gen-2021 Rospiccio M.Arsiccio A.Pisano R. + a-2021_MP_18(1)_2322-2333.pdfa-2021_MP_18(1)_2322-2333_(AAM).pdf
A model-based approach for the rational design of the freeze-thawing of a protein-based formulation / Arsiccio, A.; Marenco, L.; Pisano, R.. - In: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. - ISSN 1083-7450. - STAMPA. - 25:7(2020), pp. 823-831. [10.1080/10837450.2020.1743719] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_PDT_25(7)_823-831_(post-print).pdfa-2020_PDT_25(7)_823-831.pdf
ADD force field for sugars and polyols: predicting the additivity of protein-osmolyte interaction / Arsiccio, A.; Ganguly, P.; La Cortiglia, L.; Shea, J. -E.; Pisano, R.. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 124:36(2020), pp. 7779-7790. [10.1021/acs.jpcb.0c05345] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_JPCB_124(36)_7779-7790_(post-print).pdfa-2020_JPCB_124(36)_7779-7790.pdf
Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach / Arsiccio, A.; Giorsello, P.; Marenco, L.; Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 464-475. [10.1016/j.xphs.2019.10.022] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_109(1)_464-475.pdfa-2020_109(1)_464-475_(post-print).pdf
Freeze Drying of Therapeutic Proteins: A Simulation Approach to Optimize Formulation and Process Conditions / Arsiccio, Andrea. - (2020 Feb 13), pp. 1-286. 13-feb-2020 ARSICCIO, ANDREA thesis-pdfA.pdfSummary.pdf
Heightened cold-denaturation of proteins at the ice-water interface / Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - 142:12(2020), pp. 5722-5730. [10.1021/jacs.9b13454] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_JACS_142(12)_5722-5730.pdf
Impact of controlled vacuum induced surface freezing on the freeze drying of human plasma / Arsiccio, A.; Matejtschuk, P.; Ezeajughi, E.; Riches-Duit, A.; Bullen, A.; Malik, K.; Raut, S.; Pisano, R.. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - STAMPA. - 582:(2020), p. 119290. [10.1016/j.ijpharm.2020.119290] 1-gen-2020 Arsiccio A.Pisano R. + a-2020_IJP_582_119290_(post-print).pdfa-2020_IJP_582_119290.pdf
The ice-water interface and protein stability: a review / Arsiccio, A.; Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:7(2020), pp. 2116-2130. [10.1016/j.xphs.2020.03.022] 1-gen-2020 Arsiccio A.Pisano R. a-2020_JPS_109(7)_2116-2130_(post-print).pdfa-2020_JPS_109(7)_2116-2130.pdf
Vacuum-induced surface freezing for the freeze-drying of the Human Growth Hormone: how does nucleation control affect protein stability? / Oddone, I.; Arsiccio, A.; Duru, C.; Malik, K.; Ferguson, J.; Pisano, R.; Matejtschuk, P.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 254-263. [10.1016/j.xphs.2019.04.014] 1-gen-2020 Oddone I.Arsiccio A.Pisano R. + a-2020_JPS_109(1)_254-263.pdf
A design space approach for the freezing step of freeze-drying: considerations for process performance and protein stability / Arsiccio, Andrea; Pisano, Roberto. - STAMPA. - (2019). (Intervento presentato al convegno 7th European Conference “EuroDrying’2019” tenutosi a Torino nel July 10-12, 2019). 1-gen-2019 Andrea ArsiccioRoberto Pisano 48_ED2019_arsiccio_DS.pdf
A proximity-based in silico approach to identify redox-labile disulfide bonds: the example of FVIII / Arsiccio, A.; Metcalfe, C.; Riches, A.; Pisano, R.; Raut, S.; Coxon, C.. - ELETTRONICO. - (2019). (Intervento presentato al convegno ISTH 2019 Congress tenutosi a Melbourne, Australia nel July 6-10). 1-gen-2019 Arsiccio A.Pisano R. + -