Archivio Istituzionale della RicercaARSICCIO, ANDREA
A design space approach for the freezing step of freeze-drying: considerations for process performance and protein stability
2019 Arsiccio, Andrea; Pisano, Roberto
A model-based approach for the rational design of the freeze-thawing of a protein-based formulation
2020 Arsiccio, A.; Marenco, L.; Pisano, R.
A new transfer free energy based implicit solvation model for the description of disordered and folded proteins
2022 Arsiccio, Andrea; Pisano, Roberto; Shea, Joan-Emma
A proximity-based in silico approach to identify redox-labile disulfide bonds: the example of FVIII
2019 Arsiccio, A.; Metcalfe, C.; Riches, A.; Pisano, R.; Raut, S.; Coxon, C.
A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII
2022 Arsiccio, Andrea; Metcalfe, Clive; Pisano, Roberto; Raut, Sanj; Coxon, Carmen
Achieving continuous manufacturing in lyophilization: technologies and approaches
2019 Pisano, R.; Arsiccio, A.; Capozzi, L. C.; Trout, B. L.
ADD force field for sugars and polyols: predicting the additivity of protein-osmolyte interaction
2020 Arsiccio, A.; Ganguly, P.; La Cortiglia, L.; Shea, J. -E.; Pisano, R.
Application of the Quality by Design approach to the freezing step of freeze-drying: building the design space
2018 Arsiccio, Andrea; Pisano, Roberto
Clarifying the role of cryo- and lyo-protectants in the biopreservation of proteins
2018 Arsiccio, Andrea; Pisano, Roberto
Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach
2020 Arsiccio, A.; Giorsello, P.; Marenco, L.; Pisano, R.
Design of the formulation for therapeutic proteins. How to improve stability of drugs during freezing and in the dried state
2018 Arsiccio, Andrea; Pisano, Roberto
Designing the optimal formulation for biopharmaceuticals: a new approach combining molecular dynamics and experiments
2019 Arsiccio, Andrea; Paladini, Andrea; Pattarino, Franco; Pisano, Roberto
Effect of diffusion kinetics on the ice nucleation temperature distribution
2022 Stratta, Lorenzo; Arsiccio, Andrea; Pisano, Roberto
Effect of Surfactants on Surface-Induced Denaturation of Proteins: An Insight from Molecular Dynamics
2019 Arsiccio, Andrea; Mccarty, James; Shea, Joan-Emma; Pisano, Roberto
Effect of surfactants on surface-induced denaturation of proteins: evidence of an orientation-dependent mechanism
2018 Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.
Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins
2021 Arsiccio, Andrea; Rospiccio, Marcello; Shea, Joan-Emma; Pisano, Roberto
Formulation design and optimization using molecular dynamics
2019 Pisano, Roberto; Arsiccio, Andrea
Freeze Drying of Therapeutic Proteins: A Simulation Approach to Optimize Formulation and Process Conditions
2020 Arsiccio, Andrea
Heightened cold-denaturation of proteins at the ice-water interface
2020 Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.
Image segmentation and 3D reconstruction for improved prediction of the sublimation rate during freeze drying
2018 Capozzi, L. C.; Arsiccio, A.; Sparavigna, A. C.; Pisano, R.; Barresi, A. A.
| Citazione | Data di pubblicazione | Autori | File |
|---|---|---|---|
| A design space approach for the freezing step of freeze-drying: considerations for process performance and protein stability / Arsiccio, Andrea; Pisano, Roberto. - STAMPA. - (2019). (Intervento presentato al convegno 7th European Conference “EuroDrying’2019” tenutosi a Torino nel July 10-12, 2019). | 1-gen-2019 | Andrea ArsiccioRoberto Pisano | 48_ED2019_arsiccio_DS.pdf |
| A model-based approach for the rational design of the freeze-thawing of a protein-based formulation / Arsiccio, A.; Marenco, L.; Pisano, R.. - In: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. - ISSN 1083-7450. - STAMPA. - 25:7(2020), pp. 823-831. [10.1080/10837450.2020.1743719] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_PDT_25(7)_823-831_(post-print).pdf; a-2020_PDT_25(7)_823-831.pdf |
| A new transfer free energy based implicit solvation model for the description of disordered and folded proteins / Arsiccio, Andrea; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - 126:33(2022), pp. 6180-6190. [10.1021/acs.jpcb.2c03980] | 1-gen-2022 | Arsiccio, AndreaPisano, Roberto + | a-2022_JPCB_126_6180-6190.pdf |
| A proximity-based in silico approach to identify redox-labile disulfide bonds: the example of FVIII / Arsiccio, A.; Metcalfe, C.; Riches, A.; Pisano, R.; Raut, S.; Coxon, C.. - ELETTRONICO. - (2019). (Intervento presentato al convegno ISTH 2019 Congress tenutosi a Melbourne, Australia nel July 6-10). | 1-gen-2019 | Arsiccio A.Pisano R. + | - |
| A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII / Arsiccio, Andrea; Metcalfe, Clive; Pisano, Roberto; Raut, Sanj; Coxon, Carmen. - In: PLOS ONE. - ISSN 1932-6203. - 17:2(2022), pp. 1-24. [10.1371/journal.pone.0262409] | 1-gen-2022 | Arsiccio, AndreaPisano, Roberto + | a-2022_PO_17(2)_e0262409.pdf |
| Achieving continuous manufacturing in lyophilization: technologies and approaches / Pisano, R.; Arsiccio, A.; Capozzi, L. C.; Trout, B. L.. - In: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. - ISSN 0939-6411. - STAMPA. - 142:(2019), pp. 265-279. [10.1016/j.ejpb.2019.06.027] | 1-gen-2019 | Pisano R.Arsiccio A.Capozzi L. C. + | a-2019_EJPB_142(1)_265-279.pdf |
| ADD force field for sugars and polyols: predicting the additivity of protein-osmolyte interaction / Arsiccio, A.; Ganguly, P.; La Cortiglia, L.; Shea, J. -E.; Pisano, R.. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 124:36(2020), pp. 7779-7790. [10.1021/acs.jpcb.0c05345] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_JPCB_124(36)_7779-7790_(post-print).pdf; a-2020_JPCB_124(36)_7779-7790.pdf |
| Application of the Quality by Design approach to the freezing step of freeze-drying: building the design space / Arsiccio, Andrea; Pisano, Roberto. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 107:6(2018), pp. 1586-1596. [10.1016/j.xphs.2018.02.003] | 1-gen-2018 | Arsiccio, AndreaPisano, Roberto | a-2018_JPS_107(6)_1586-1596.pdf |
| Clarifying the role of cryo- and lyo-protectants in the biopreservation of proteins / Arsiccio, Andrea; Pisano, Roberto. - In: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. - ISSN 1463-9076. - STAMPA. - 20:12(2018), pp. 8267-8277. [10.1039/c7cp08029h] | 1-gen-2018 | Arsiccio, AndreaPisano, Roberto | - |
| Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach / Arsiccio, A.; Giorsello, P.; Marenco, L.; Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 464-475. [10.1016/j.xphs.2019.10.022] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_109(1)_464-475.pdf; a-2020_109(1)_464-475_(post-print).pdf |
| Design of the formulation for therapeutic proteins. How to improve stability of drugs during freezing and in the dried state / Arsiccio, Andrea; Pisano, Roberto. - In: CHIMICA OGGI-CHEMISTRY TODAY. - ISSN 0392-839X. - STAMPA. - 36:5(2018), pp. 16-18. | 1-gen-2018 | Arsiccio, AndreaPisano, Roberto | - |
| Designing the optimal formulation for biopharmaceuticals: a new approach combining molecular dynamics and experiments / Arsiccio, Andrea; Paladini, Andrea; Pattarino, Franco; Pisano, Roberto. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 108:1(2019), pp. 431-438. [10.1016/j.xphs.2018.09.002] | 1-gen-2019 | Arsiccio, AndreaPaladini, AndreaPisano, Roberto + | a-2019_JPS_108(1)_431-438.pdf |
| Effect of diffusion kinetics on the ice nucleation temperature distribution / Stratta, Lorenzo; Arsiccio, Andrea; Pisano, Roberto. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 12:(2022), pp. 1-10. [10.1038/s41598-022-20797-1] | 1-gen-2022 | Stratta, LorenzoArsiccio, AndreaPisano, Roberto | a-2022_SR_12_16334.pdf |
| Effect of Surfactants on Surface-Induced Denaturation of Proteins: An Insight from Molecular Dynamics / Arsiccio, Andrea; Mccarty, James; Shea, Joan-Emma; Pisano, Roberto. - STAMPA. - (2019). (Intervento presentato al convegno 2019 Colorado Protein Stability Conference - 25th Anniversary tenutosi a Breckenridge, Colorado, USA nel July 29 - August 1). | 1-gen-2019 | Arsiccio, AndreaPisano, Roberto + | Abstract-ProteinStabilityConference-Arsiccio.pdf |
| Effect of surfactants on surface-induced denaturation of proteins: evidence of an orientation-dependent mechanism / Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 122:49(2018), pp. 11390-11399. [10.1021/acs.jpcb.8b07368] | 1-gen-2018 | Arsiccio A.Pisano R. + | - |
| Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins / Arsiccio, Andrea; Rospiccio, Marcello; Shea, Joan-Emma; Pisano, Roberto. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 125:27(2021), pp. 7397-7405. [10.1021/acs.jpcb.1c04033] | 1-gen-2021 | Arsiccio, AndreaRospiccio, MarcelloPisano, Roberto + | acs.jpcb.1c04033.pdf |
| Formulation design and optimization using molecular dynamics / Pisano, Roberto; Arsiccio, Andrea - In: Freeze-Drying of Pharmaceutical Products / Fissore D., Pisano R., Barresi A. A.. - STAMPA. - Boca Raton (Florida), USA : CRC Press, 2019. - ISBN 978-0367076801. - pp. 11-31 [http://dx.doi.org/10.1201/9780429022074-1] | 1-gen-2019 | Pisano, RobertoArsiccio, Andrea | b-2019_CRC_FDPP_c2.pdf |
| Freeze Drying of Therapeutic Proteins: A Simulation Approach to Optimize Formulation and Process Conditions / Arsiccio, Andrea. - (2020 Feb 13), pp. 1-286. | 13-feb-2020 | ARSICCIO, ANDREA | thesis-pdfA.pdf; Summary.pdf |
| Heightened cold-denaturation of proteins at the ice-water interface / Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - 142:12(2020), pp. 5722-5730. [10.1021/jacs.9b13454] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_JACS_142(12)_5722-5730.pdf |
| Image segmentation and 3D reconstruction for improved prediction of the sublimation rate during freeze drying / Capozzi, L. C.; Arsiccio, A.; Sparavigna, A. C.; Pisano, R.; Barresi, A. A.. - STAMPA. - (2018), pp. 411-418. (Intervento presentato al convegno IDS’2018 – 21st International Drying Symposium tenutosi a Valencia, Spain nel 11-14 September 2018) [http://dx.doi.org/10.4995/IDS2018.2018.8877]. | 1-gen-2018 | Capozzi L. C.Arsiccio A.Sparavigna A. C.Pisano R.Barresi A. A. | 2018_IDS2018_Image-segmentation-FD_cover.pdf |