PISANO, ROBERTO

PISANO, ROBERTO  

Dipartimento Scienza Applicata e Tecnologia  

015508  

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Shear stress as a driver of degradation for protein-based therapeutics: More accomplice than culprit / Moino, Camilla; Artusio, Fiora; Pisano, Roberto. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - 650:(2024), pp. 1-15. [10.1016/j.ijpharm.2023.123679] 1-gen-2024 Moino, CamillaArtusio, FioraPisano, Roberto Shear stress as a driver of degradation for protein.based therapeutics. more accomplice than culprit.pdf
A diffused-interface model for the lyophilization of a packed bed of spray-frozen particles / Stratta, Lorenzo; Adali, Merve B.; Barresi, Antonello A.; Boccardo, Gianluca; Marcato, Agnese; Tuccinardi, Raffaele; Pisano, Roberto. - In: CHEMICAL ENGINEERING SCIENCE. - ISSN 0009-2509. - STAMPA. - 275:(2023), pp. 1-14. [10.1016/j.ces.2023.118726] 1-gen-2023 Lorenzo StrattaMerve B. AdaliAntonello A. BarresiGianluca BoccardoAgnese MarcatoRoberto Pisano + 2023_CES_275-118726_Diffuse_interface_packed-bed_lyophilization.pdf2023_CES_SFD_postprint_Authors_accepted_manuscript.pdf
Advances in ascorbic acid (vitamin C) manufacturing: green extraction techniques from natural sources / Susa, Francesca; Pisano, Roberto. - In: PROCESSES. - ISSN 2227-9717. - STAMPA. - 11:11(2023), pp. 1-17. [10.3390/pr11113167] 1-gen-2023 Susa, FrancescaPisano, Roberto a-2023_PROCESSES_11_03167.pdf
Analysis of the Shear Stresses in a Filling Line of Parenteral Products: The Role of Fittings / Moino, C; Scutella, B; Bellini, M; Bourles, E; Boccardo, G; Pisano, R. - In: PROCESSES. - ISSN 2227-9717. - 11:6(2023), pp. 1-20. [10.3390/pr11061797] 1-gen-2023 Moino, CBoccardo, GPisano, R + processes-11-01797-v2 (3).pdf
Analysis of the Shear Stresses in a Filling Line of Parenteral Products: The Role of Tubing / Moino, C; Scutella, B; Bellini, M; Bourles, E; Boccardo, G; Pisano, R. - In: PROCESSES. - ISSN 2227-9717. - 11:3(2023). [10.3390/pr11030833] 1-gen-2023 Moino, CBoccardo, GPisano, R + Analysis of the shear stresses in a filling line of parenteral products. the role of tubing.pdf
Comparative Studies of Different Preservation Methods and Relative Freeze-Drying Formulations for Extracellular Vesicle Pharmaceutical Applications / Susa, Francesca; Limongi, Tania; Borgione, Francesca; Peiretti, Silvia; Vallino, Marta; Cauda, Valentina; Pisano, Roberto. - In: ACS BIOMATERIALS SCIENCE & ENGINEERING. - ISSN 2373-9878. - 9:10(2023), pp. 5871-5885. [10.1021/acsbiomaterials.3c00678] 1-gen-2023 Susa, FrancescaLimongi, TaniaCauda, ValentinaPisano, Roberto + susa-et-al-2023-comparative-studies-of-different-preservation-methods-and-relative-freeze-drying-formulations-for.pdf
Freeze-Drying of Pharmaceuticals in Vials Nested in a Rack System — Part I: Freezing Behaviour / Pisano, Roberto; Artusio, Fiora; Adami, Marco; Barresi, Antonello A.; Fissore, Davide; Frare, Maria Chiara; Zanetti, Francesco; Zunino, Gabriele. - In: PHARMACEUTICS. - ISSN 1999-4923. - ELETTRONICO. - 15:2(2023). [10.3390/pharmaceutics15020635] 1-gen-2023 Pisano, RobertoArtusio, FioraBarresi, Antonello A.Fissore, Davide + 108.P_2023_vol15.pdf
Mechanistic Investigation of tert-Butanol’s Impact on Biopharmaceutical Formulations: When Experiments Meet Molecular Dynamics / Rospiccio, Marcello; Casucci, Paola; Arsiccio, Andrea; Udrescu, Claudia; Pisano, Roberto. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8392. - ELETTRONICO. - 20:8(2023), pp. 3975-3986. [10.1021/acs.molpharmaceut.3c00125] 1-gen-2023 Marcello RospiccioPaola CasucciAndrea ArsiccioClaudia UdrescuRoberto Pisano acs.molpharmaceut.3c00125.pdfmp3c00125_si_001.pdf
New trends in freeze-drying of pharmaceutical products / Pisano, R.; Fissore, D.. - In: PHARMACEUTICS. - ISSN 1999-4923. - ELETTRONICO. - 15:7(2023), p. 1975. [10.3390/pharmaceutics15071975] 1-gen-2023 Pisano R.Fissore D. 111.P_2023_vol15.pdf
On the use of temperature measurements as a Process Analytical Technology (PAT) for the monitoring of a pharmaceutical freeze-drying process / Vallan, Alberto; Fissore, Davide; Pisano, Roberto; Barresi, Antonello A.. - In: PHARMACEUTICS. - ISSN 1999-4923. - ELETTRONICO. - 15:3(2023). [10.3390/pharmaceutics15030861] 1-gen-2023 Alberto VallanDavide FissoreRoberto PisanoAntonello A. Barresi pharmaceutics-15-00861.pdf
Self-assembled monolayers as a tool to investigate the effect of surface chemistry on protein nucleation / Artusio, Fiora; Gavira, José A; Pisano, Roberto. - In: CRYSTAL GROWTH & DESIGN. - ISSN 1528-7483. - 23:5(2023), pp. 3195-3201. [10.1021/acs.cgd.2c01377] 1-gen-2023 Artusio, FioraPisano, Roberto + a-2023_CGD_23(5)_3195-3201.pdf
Tailoring dry microparticles for pulmonary drug delivery: ultrasonic spray freeze-drying with mannitol and salbutamol sulphate / Pasero, Lorena; Susa, Francesca; Chiavarino, Riccardo; Limongi, Tania; Sulpizi, Adamo; Guidi, Tomaso; Pisano, Roberto. - In: PROCESSES. - ISSN 2227-9717. - STAMPA. - 11:11(2023). [10.3390/pr11113096] 1-gen-2023 Lorena PaseroFrancesca SusaTania LimongiRoberto Pisano + a-2023_PROCESSES-11-03096.pdf
The freeze-drying of pharmaceuticals in vials nested in a rack system. – Part II: Primary drying behaviour / Artusio, F.; Adami, M.; Barresi, A. A.; Fissore, D.; Frare, M. C.; Udrescu, C. I.; Pisano, R.. - In: PHARMACEUTICS. - ISSN 1999-4923. - ELETTRONICO. - 15:11(2023). [10.3390/pharmaceutics15112570] 1-gen-2023 Artusio F.Barresi A. A.Fissore D.Udrescu C. I.Pisano R. + pharmaceutics-15-02570.pdf
Thermodynamic modeling and experimental data reveal that sugars stabilize proteins according to an excluded volume mechanism / Arsiccio, Andrea; Sarter, Tim; Polidori, Ilaria; Winter, Gerhard; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 1520-5126. - 145:30(2023), pp. 16678-16690. [10.1021/jacs.3c04293] 1-gen-2023 Andrea ArsiccioRoberto Pisano + a-2023_JACS_145(30)_16678-16690.pdfa-2023_JACS_145(30)_16678-16690_(pre-print).pdf
Ultrasonic spray freeze-drying of sucrose and mannitol-based formulations: impact of the atomization conditions on the particle morphology and drying performance / Adali, M. B.; Barresi, A.; Boccardo, G.; Montalbano, G.; Pisano, R.. - In: DRYING TECHNOLOGY. - ISSN 0737-3937. - STAMPA. - 41:2(2023), pp. 251-261. [10.1080/07373937.2021.2024844] 1-gen-2023 Adali M. B.Barresi A.Boccardo G.Montalbano G.Pisano R. 03_DT_SFDexp_Manuscript_(R1).pdf2023_DT_41(2)_USFD-morphology.pdf
A new transfer free energy based implicit solvation model for the description of disordered and folded proteins / Arsiccio, Andrea; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - 126:33(2022), pp. 6180-6190. [10.1021/acs.jpcb.2c03980] 1-gen-2022 Arsiccio, AndreaPisano, Roberto + a-2022_JPCB_126_6180-6190.pdf
A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII / Arsiccio, Andrea; Metcalfe, Clive; Pisano, Roberto; Raut, Sanj; Coxon, Carmen. - In: PLOS ONE. - ISSN 1932-6203. - 17:2(2022), pp. 1-24. [10.1371/journal.pone.0262409] 1-gen-2022 Arsiccio, AndreaPisano, Roberto + a-2022_PO_17(2)_e0262409.pdf
An experimental and modeling combined approach in preparative Hydrophobic Interaction Chromatography / Lietta, Elena; Pieri, Alessandro; Cardillo, Antonio G.; Vanni, Marco; Pisano, Roberto; Barresi, Antonello A.. - In: PROCESSES. - ISSN 2227-9717. - ELETTRONICO. - 10:5(2022), p. 1027. [10.3390/pr10051027] 1-gen-2022 Elena LiettaMarco VanniRoberto PisanoAntonello A. Barresi + 2022_processes-10-01027_preparative_chromatography.pdf
Automatic control of a freeze-drying process: Detection of the end point of primary drying / Pisano, R.. - In: DRYING TECHNOLOGY. - ISSN 0737-3937. - STAMPA. - 40:1(2022), pp. 140-157. [10.1080/07373937.2020.1774891] 1-gen-2022 Pisano R. a-2022_DT_40(1)_140-157.pdf
Bacterial ligands as flexible and sensitive detectors in rapid tests for antibodies to SARS-CoV-2 / Cavalera, Simone; Di Nardo, Fabio; Chiarello, Matteo; Serra, Thea; Colitti, Barbara; Guiotto, Cristina; Fagioli, Franca; Cagnazzo, Celeste; Denina, Marco; Palazzo, Annagloria; Artusio, Fiora; Pisano, Roberto; Rosati, Sergio; Baggiani, Claudio; Anfossi, Laura. - In: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. - ISSN 1618-2642. - 414:18(2022), pp. 5473-5482. [10.1007/s00216-022-03939-2] 1-gen-2022 Artusio, FioraPisano, Roberto + a-2022_ABC_414_5473-5482.pdf