A review on computational tools for analytical visualisation and molecular interactions of sncRNAs: prospects in NDDs

Neurodevelopmental disorders (NDD) including cognitive impairments, motor disabilities, and psychoso- cial disorders are common among infants that are born prematurely, but the molecular mechanisms behind them are still not clear. Nevertheless, recent studies have shown that there are some shared molecular pathways driving NDDs and neurodegenerative diseases with sncRNAs having a significant role in their manifestation. It is important to study and reveal the mechanism behind the development of these disorders to predict them as soon as possible, using biomarkers and allowing medical doctors to intervene early on, while neuroplasticity in newborns still allows for recovery to some extent. In this work, we examine the role of sncRNAs and some of the shared pathways in NDDs, but most importantly, we present some of the existing computational tools and databases for predicting target interactions, and tools to perform network analysis and visualization.