Organic Electrochemical Transistors (OECTs) represent a versatile tool successfully exploited in the field of Bioelectronics. In particular, OECTs have been used for the detection of a wide set of bioanalytes, often showing superior performance compared to that of commonly used sensors. In this study, we propose a flexible, disposable OECT, based on poly (3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) channels and few layers graphene (FLG) sheets gate electrodes, for the detection of Tamoxifen (TAM), an important antitumor drug widely used in breast cancer therapy. The optimal device operation conditions in terms of sensitivity and limit of detection (LOD) have been investigated too.

Nanomolar detection of the antitumor drug tamoxifen by flexible organic electrochemical devices / D'Angelo, P.; Tarabella, G.; Romeo, A.; Marasso, S. L.; Cocuzza, M.; Peruzzi, C.; Vurro, D.; Carotenuto, G.; Iannotta, S.. - In: AIP CONFERENCE PROCEEDINGS. - ISSN 0094-243X. - ELETTRONICO. - 1990:(2018), p. 020015. ((Intervento presentato al convegno 2nd NanoInnovation 2017 Conference and Exhibition tenutosi a ita nel 2017 [10.1063/1.5047769].

Nanomolar detection of the antitumor drug tamoxifen by flexible organic electrochemical devices

Marasso S. L.;Cocuzza M.;Iannotta S.
2018

Abstract

Organic Electrochemical Transistors (OECTs) represent a versatile tool successfully exploited in the field of Bioelectronics. In particular, OECTs have been used for the detection of a wide set of bioanalytes, often showing superior performance compared to that of commonly used sensors. In this study, we propose a flexible, disposable OECT, based on poly (3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) channels and few layers graphene (FLG) sheets gate electrodes, for the detection of Tamoxifen (TAM), an important antitumor drug widely used in breast cancer therapy. The optimal device operation conditions in terms of sensitivity and limit of detection (LOD) have been investigated too.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2860916