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EnglishThe continuing discovery of new functions and classes of small non-coding RNAs is suggesting the presence of regulatory mechanisms far more complex than the ones identified so far. In our computational analysis of a large set of public available databases, we found statistical evidence of an inter-pathway regulatory motif, not previously described, that reveals a new protective role miRNAs may play in the successful activation of a pathway. This paper reports the main outcomes of this analysis.
A New miRNA Motif Protects Pathways’ Expression in Gene Regulatory Networks / Benso A.; Di Carlo S.; Politano G.; Savino A.. - STAMPA. - (2013), pp. 377-384. ((Intervento presentato al convegno International Work-Conference on Bioinformatics and Biomedical Engineering (IWBBIO) tenutosi a Granada, ES nel 18-20 March , 2013.
| Titolo: | A New miRNA Motif Protects Pathways’ Expression in Gene Regulatory Networks | |
| Autori: | ||
| Data di pubblicazione: | 2013 | |
| Abstract: | The continuing discovery of new functions and classes of small non-coding RNAs is suggesting the ...presence of regulatory mechanisms far more complex than the ones identified so far. In our computational analysis of a large set of public available databases, we found statistical evidence of an inter-pathway regulatory motif, not previously described, that reveals a new protective role miRNAs may play in the successful activation of a pathway. This paper reports the main outcomes of this analysis. | |
| Appare nelle tipologie: | 4.1 Contributo in Atti di convegno |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| 2013-IWBBIO-PPL.pdf | This PDF is publicly available on the web | 2. Post-print / Author's Accepted Manuscript | PUBBLICO - Tutti i diritti riservati | Visibile a tuttiVisualizza/Apri |
http://hdl.handle.net/11583/2518694
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