Impedance cardiography assessment during body immersion in a high concentrated water solution of magnesium chloride simulating space microgravity: a pilot study

In 14 healthy subjects (9 males and 5 females, 32±15 years) a beat-by-beat cardiodynamic profile was acquired with impedance cardiography during 10 minutes while lying supine and relaxed in a bed and then in a bath tub with a high concentration of MgCl2 reaching density 1/3 times more than sea. While in the tub, an increase in ventricular preload index (+47%) with reduction in contractility (-17%) and arterial pressure (-5%) occurred like as in space flights. So this method could be seen as a new way to simulating space fly at ground.