System Integration of an Implantable Drug Delivery Device for Long-Term In-Vivo Experiments

The Nanochannel Delivery System (nDS) is a remotely-controlled active drug delivery device intended to treat chronic diseases. This work is focused on system integration and characterization towards long-term in-vivo experiments on sustained drug release. The design included a wireless charging system, improved release control system, and the introduction of temperature sensing. The engineering process prioritized compactness and energy efficiency, and its results, concerning improved functionality, energetic efficiency, and communication performance indicated compliance with biocompatibility and functional requirements set by chronic experiments lasting years.