Archivio Istituzionale della RicercaThis project aims at reproducing the morphology and the composition of the pancreatic acino-ductal unit. More specifically, this work involves the use of a 4D printing system that combines melt electrospinning technology with an automatized layer-by-layer surface functionalization which provides biological cues to the surface of the melt electrospun structure. This 3D exocrine glandular tissue model mimics in vitro the physiological structure experienced by cells in vivo and serves as a powerful tool to investigate pathological processes such as the Pancreatic Ductal Adenocarcinoma (PDAC).
4D Printing to fabricate an in vitro model of the pancreatic acino ductal unit / Sgarminato, Viola; TONDA TURO, Chiara; Ciardelli, Gianluca. - (2020), pp. 193-194. (Intervento presentato al convegno 2a Conferenza Italiana di Robotica e Macchine Intelligenti tenutosi a Rome, Italy (virtual) nel 10-12 Dicembre 2020) [10.5281/zenodo.4781362].
4D Printing to fabricate an in vitro model of the pancreatic acino ductal unit
Sgarminato, Viola;Tonda-Turo Chiara;Ciardelli Gianluca
2020
Abstract
This project aims at reproducing the morphology and the composition of the pancreatic acino-ductal unit. More specifically, this work involves the use of a 4D printing system that combines melt electrospinning technology with an automatized layer-by-layer surface functionalization which provides biological cues to the surface of the melt electrospun structure. This 3D exocrine glandular tissue model mimics in vitro the physiological structure experienced by cells in vivo and serves as a powerful tool to investigate pathological processes such as the Pancreatic Ductal Adenocarcinoma (PDAC).
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https://hdl.handle.net/11583/2988248