Migrating cells measure the external environment through receptor-binding of specific chemicals at their outer cell membrane. In this paper this non-local sampling is incorporated into a chemotactic model. The existence of global bounded solutions of the non-local model is proven for bounded and unbounded domains in any space dimension. According to a recent classification of spikes and plateaus, it is shown that steady state solutions cannot be of spike-type. Finally, numerical simulations support the theoretical results, illustrating the ability of the model to give rise to pattern formation. Some biologically relevant extensions of the model are also considered.
Global existence for chemotaxis with finite sampling radius / Hillen, T.; Painter, K.; Schmeiser, C.. - In: DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS. SERIES B.. - ISSN 1531-3492. - 7:1(2007), pp. 125-144. [10.3934/dcdsb.2007.7.125]
Global existence for chemotaxis with finite sampling radius
Hillen T.;Painter K.;
2007
Abstract
Migrating cells measure the external environment through receptor-binding of specific chemicals at their outer cell membrane. In this paper this non-local sampling is incorporated into a chemotactic model. The existence of global bounded solutions of the non-local model is proven for bounded and unbounded domains in any space dimension. According to a recent classification of spikes and plateaus, it is shown that steady state solutions cannot be of spike-type. Finally, numerical simulations support the theoretical results, illustrating the ability of the model to give rise to pattern formation. Some biologically relevant extensions of the model are also considered.File | Dimensione | Formato | |
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https://hdl.handle.net/11583/2974230