The aim of the work is to propose a methodology for the stimulation of a 3D in vitro skin model to activate wound healing. The presented work is in the frame of the national research project, CronXCov, “Checking the CHRONIC to prevent COVID-19”, devoted to understand how physiologic and inflamed skin on chip 3D models evolve upon a range of physical (e.g., electrical, mechanical, optical) stimulations, over time. Thanks to the 3D modelling, using Next Generation Sequencing and the network medicine frame of analysis to process the data, we will systematically characterize the effects of the applied stimuli, offering new insight for the exploitation of wound healing.

Electrostimulation of a 3D in vitro skin model to activate wound healing / Villata, Simona; Napione, Lucia; Baruffaldi, Désirée; Nardini, Christine; Frascella, Francesca; Pirri, Fabrizio. - In: BIOMEDICAL SCIENCE AND ENGINEERING. - ISSN 2531-9892. - ELETTRONICO. - 4 s1:(2021), pp. 119-120. ((Intervento presentato al convegno III Convegno Annuale "L'era delle 3R: modelli in silico, in vitro e in vivo per promuovere la ricerca traslazionale" tenutosi a evento online nel 30 Settembre - 1 Ottobre 2021 [10.4081/bse.2021.200].

Electrostimulation of a 3D in vitro skin model to activate wound healing

Villata, Simona;Napione, Lucia;Baruffaldi, Désirée;Frascella, Francesca;Pirri, Fabrizio
2021

Abstract

The aim of the work is to propose a methodology for the stimulation of a 3D in vitro skin model to activate wound healing. The presented work is in the frame of the national research project, CronXCov, “Checking the CHRONIC to prevent COVID-19”, devoted to understand how physiologic and inflamed skin on chip 3D models evolve upon a range of physical (e.g., electrical, mechanical, optical) stimulations, over time. Thanks to the 3D modelling, using Next Generation Sequencing and the network medicine frame of analysis to process the data, we will systematically characterize the effects of the applied stimuli, offering new insight for the exploitation of wound healing.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11583/2954805