Archivio Istituzionale della RicercaPhotodynamic therapy (PDT) is a promising technique for several types of anti-cancer therapy, exploiting a photosensitizer, a light source and oxygen. The present work computationally investigates the properties of poly(amidoamine) (PAMAM) and poly(propyleneimine) (PPI) dendrimers of generation 3 and 4 as potential nanoscale drug delivery systems for Rose Bengal (RB), a candidate photosensitizer for PDT.
PAMAM and PPI dendrimers as potential anti-cancer drug carriers: a computational investigation / Zizzi, Eric A.; Pallante, Lorenzo; Miceli, Marcello; Sztandera, Krzysztof; Bątal, Mateusz; Tuszynski, Jacek A.; Deriu, Marco A.. - ELETTRONICO. - (2021). (Intervento presentato al convegno CANCERTO - NANOSCIENCE IN CANCER IMMUNOTHERAPY nel March 9–11, 2021) [10.3389/978-2-88966-543-3].
PAMAM and PPI dendrimers as potential anti-cancer drug carriers: a computational investigation
Eric A. Zizzi;Lorenzo Pallante;Marcello Miceli;Jacek A. Tuszynski;Marco A. Deriu
2021
Abstract
Photodynamic therapy (PDT) is a promising technique for several types of anti-cancer therapy, exploiting a photosensitizer, a light source and oxygen. The present work computationally investigates the properties of poly(amidoamine) (PAMAM) and poly(propyleneimine) (PPI) dendrimers of generation 3 and 4 as potential nanoscale drug delivery systems for Rose Bengal (RB), a candidate photosensitizer for PDT.
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https://hdl.handle.net/11583/2940092