This work shows an alternative pharmaceutical freeze-drying concept, which makes it possible to move from batch to continuous manufacturing. The continuous flow of vials is achieved by suspending them over a moving track. The vials move through chambers which have different pressure and temperature conditions and are separated by a load-lock system. Uniformity in freezing conditions is demonstrated by combining the Vacuum Induced Surface Freezing method and convective freezing.
Modernizing lyophilization of pharmaceuticals in unit doses via continuous manufacturing / Pisano, Roberto. - STAMPA. - (2019), pp. 14-15. ((Intervento presentato al convegno 9th International Symposium on Lyophilization of Pharmaceuticals tenutosi a Ghent nel September 2-6, 2019.
Titolo: | Modernizing lyophilization of pharmaceuticals in unit doses via continuous manufacturing | |
Autori: | ||
Data di pubblicazione: | 2019 | |
Abstract: | This work shows an alternative pharmaceutical freeze-drying concept, which makes it possible to m...ove from batch to continuous manufacturing. The continuous flow of vials is achieved by suspending them over a moving track. The vials move through chambers which have different pressure and temperature conditions and are separated by a load-lock system. Uniformity in freezing conditions is demonstrated by combining the Vacuum Induced Surface Freezing method and convective freezing. | |
Appare nelle tipologie: | 4.1 Contributo in Atti di convegno |
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http://hdl.handle.net/11583/2939694