Photochemical processes offer the possibility of preparing functional hydrogels under green conditions that are compatible with both synthetic and natural polymers. In this study, chitosan-based poly(ethylene) glycol (PEG) were successfully synthesized under light irradiation in aqueous medium. Kinetic studies under irradiation showed that less than 2 min were necessary to obtain fully cross-linked networks. Thermomechanical analyses and swelling experiments indicated that introduction of chitosan overall weakens the hydrogel network but can create domains of higher thermal stability than the PEG-alone structure. The resulting chitosan-PEG hydrogels demonstrated a tremendous inhibition (100%) of bacterial growth (Escherichia coli and Staphylococcus aureus). After 6 months' ageing, one of the hydrogels preserved a high antifouling activity against Escherichia coli. This interesting result, which could be correlated with the network features, demonstrates the strong potential of these photochemical methods to obtain robust bio-functional materials.
Photoinduced chitosan-PEG hydrogels with long-term antibacterial properties / Sautrot-Ba, P.; Razza, N.; Breloy, L.; Andaloussi, S. A.; Chiappone, A.; Sangermano, M.; Helary, C.; Belbekhouche, S.; Coradin, T.; Versace, D. -L.. - In: JOURNAL OF MATERIALS CHEMISTRY. B. - ISSN 2050-750X. - ELETTRONICO. - 7:42(2019), pp. 6526-6538. [10.1039/c9tb01170f]
|Titolo:||Photoinduced chitosan-PEG hydrogels with long-term antibacterial properties|
|Data di pubblicazione:||2019|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1039/c9tb01170f|
|Appare nelle tipologie:||1.1 Articolo in rivista|