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EnglishAlthough arterio-venous grafts (AVGs) are the second best option as permanent vascular access for hemodialysis, this solution is still affected by a relevant failure rate associated with neointimal hyperplasia (IH), mainly located at the venous anastomosis, where abnormal hemodynamics occurs. In this study we use computational fluid dynamics (CFD) to investigate the impact of six innovative AVG designs on reducing the IH risk at the distal anastomosis in AVGs. Findings from simulations clearly show that using a helical shaped flow divider located in the venous side of the graft could assure a reduced hemodynamic risk of failure at the distal anastomosis, with a clinically irrelevant increase in pressure drop over the graft.
Exploring novel arterio-venous graft designs to reduce vascular access failure risk / De Nisco, G.; Siciliano, K.; Tasso, P.; Lodi Rizzini, M.; Mazzi, V.; Calò, K.; Antonucci, M.; Gallo, D.; Morbiducci, U.. - ELETTRONICO. - (2019), pp. 137-138. ((Intervento presentato al convegno ESB-ITA 2019 IX Annual Meeting tenutosi a Bologna nel 30/09/2019 - 01/10/2019.
| Titolo: | Exploring novel arterio-venous graft designs to reduce vascular access failure risk | |
| Autori: | ||
| Data di pubblicazione: | 2019 | |
| Abstract: | Although arterio-venous grafts (AVGs) are the second best option as permanent vascular access for... hemodialysis, this solution is still affected by a relevant failure rate associated with neointimal hyperplasia (IH), mainly located at the venous anastomosis, where abnormal hemodynamics occurs. In this study we use computational fluid dynamics (CFD) to investigate the impact of six innovative AVG designs on reducing the IH risk at the distal anastomosis in AVGs. Findings from simulations clearly show that using a helical shaped flow divider located in the venous side of the graft could assure a reduced hemodynamic risk of failure at the distal anastomosis, with a clinically irrelevant increase in pressure drop over the graft. | |
| Appare nelle tipologie: | 4.1 Contributo in Atti di convegno |
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| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| Giuseppe_De Nisco1_ESBITA2019.pdf | Abstract - ESB ITA 2019 | Abstract | PUBBLICO - Tutti i diritti riservati | Visibile a tuttiVisualizza/Apri |
http://hdl.handle.net/11583/2763272
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