Monitoring of patient response to the anaesthetic drugs is an attractive improvement for achieving a correct balance of sedation level, increasing the chance of success in the right procedure of anaesthesia. Nowadays, there are no commercial tools able to offer real-time monitoring of anaesthetics, indeed, there is still a lack in sensing technologies able to maintain high performances in long term monitoring within a portable miniaturised hardware system. To overcome these limitations, we are here presenting the innovative concept of a portable pen-device able to sense anaesthetic compounds over time. This study is based on an electrochemical sensor to be fully integrated into a complete pen-shaped point-of-care for the monitoringof anaesthesia delivery. The design of the system is based on a bio-inspired event-based approach that is guaranteeing low complexity, low power consumption and is therefore suitable to be scaled to fit the barrel of a pen. An exhaustive comparison between the proposed system and a lab instrument proves that the presented approach obtains comparable performances in terms of sensitivity and resolution with the ones obtained by expensive commercial instrumentation, meanwhile, the results show a 95 % power consumption reduction and a 92 % area decrease w.r.t. previously presented implementation.
Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery / Aiassa, Simone; Stradolini, Francesca; Tuoheti, Abuduwaili; Carrara, Sandro; Demarchi, Danilo. - ELETTRONICO. - 1:(2019), pp. 265-268. (Intervento presentato al convegno 2019 15th Conference on Ph.D Research in Microelectronics and Electronics (PRIME) tenutosi a Lausanne, Switzerland nel 15-18 July 2019) [10.1109/PRIME.2019.8787764].
Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery
Simone Aiassa;Abuduwaili Tuoheti;Sandro Carrara;Danilo Demarchi
2019
Abstract
Monitoring of patient response to the anaesthetic drugs is an attractive improvement for achieving a correct balance of sedation level, increasing the chance of success in the right procedure of anaesthesia. Nowadays, there are no commercial tools able to offer real-time monitoring of anaesthetics, indeed, there is still a lack in sensing technologies able to maintain high performances in long term monitoring within a portable miniaturised hardware system. To overcome these limitations, we are here presenting the innovative concept of a portable pen-device able to sense anaesthetic compounds over time. This study is based on an electrochemical sensor to be fully integrated into a complete pen-shaped point-of-care for the monitoringof anaesthesia delivery. The design of the system is based on a bio-inspired event-based approach that is guaranteeing low complexity, low power consumption and is therefore suitable to be scaled to fit the barrel of a pen. An exhaustive comparison between the proposed system and a lab instrument proves that the presented approach obtains comparable performances in terms of sensitivity and resolution with the ones obtained by expensive commercial instrumentation, meanwhile, the results show a 95 % power consumption reduction and a 92 % area decrease w.r.t. previously presented implementation.File | Dimensione | Formato | |
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https://hdl.handle.net/11583/2737410
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