SHAPES AND HEAT TRANSFER IN CANCER: THE CONSTRUCTAL RESONANCE

Any cell process requires energy, so a control of the energy conversion in the cell can represent a way to control the cell processes. Cells regulate their metabolisms by fluxes of energy and mass (ions included). The Constructal law is the thermodynamic approach which allows us to consider fluxes through the biosystems border, system shapes and interactions between biosystems and their environment in relation to the characteristic time (least time) of any process. Moreover, in relation to time, it is possible to consider the resonance phenomena. Resonance forces a natural behaviour of systems when a wave of a frequency related to the characteristic time income to a system. Here we introduce the Constructal frequency, the characteristic frequency of a system evaluated by a Constructal approach, in order to control the fluxes through the cancer membrane to force it towards a normal behaviour, by changing the concentrations of ions inside and outside the membrane itself. The consequence is a control of the metabolic processes in cells, but also a control of the energy available to cancer for its growth. In this way the cancer growth can be reduced.