A cross-flow microfluidic device has been fabricated to separate larvae of Dirofilaria species form intravenous blood sample from monolithic poly(dimethylsiloxane) (PDMS) microfluidic structure. The number of the dirofilariasis increases in veterinary cases, which disease is caused by Dirofilaria (Nochtiella) repens and Dirofilaria immitis. Each fifth pet contracts dirofilariasis in the Mediterranean region, Southern and Eastern Europe, North Africa and Asia. The zoonotic filariae, recovered commonly from humans, are found in the subcutaneous tissues, pulmonary arteries and in the right heart; the vast majority belong to the genus Dirofilaria. The utility of nematodes-filtering device is to separate larvae from the blood-steam without use of parasiticide or anthelmintic. Additionally, due to the biocompatibility of chosen materials and the hydrodynamic separation significant percent of the blood-sample is recyclable without any kind of biological modification.
Filtration of Intravenous Cardiopulmonary Parasitic Nematodes Using a Cross-Flow Microfluidic Separator / Laki, ANDRAS JOZSEF; K., Iván; Z., Fekete; P., Fürjes; Demarchi, Danilo; Civera, Pierluigi. - STAMPA. - 1:(2012), pp. 126-126. (Intervento presentato al convegno NanoBio Europe 2012 tenutosi a Varese, Italy nel 18-20 June 2012).
Filtration of Intravenous Cardiopulmonary Parasitic Nematodes Using a Cross-Flow Microfluidic Separator
LAKI, ANDRAS JOZSEF;DEMARCHI, DANILO;CIVERA, PIERLUIGI
2012
Abstract
A cross-flow microfluidic device has been fabricated to separate larvae of Dirofilaria species form intravenous blood sample from monolithic poly(dimethylsiloxane) (PDMS) microfluidic structure. The number of the dirofilariasis increases in veterinary cases, which disease is caused by Dirofilaria (Nochtiella) repens and Dirofilaria immitis. Each fifth pet contracts dirofilariasis in the Mediterranean region, Southern and Eastern Europe, North Africa and Asia. The zoonotic filariae, recovered commonly from humans, are found in the subcutaneous tissues, pulmonary arteries and in the right heart; the vast majority belong to the genus Dirofilaria. The utility of nematodes-filtering device is to separate larvae from the blood-steam without use of parasiticide or anthelmintic. Additionally, due to the biocompatibility of chosen materials and the hydrodynamic separation significant percent of the blood-sample is recyclable without any kind of biological modification.Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11583/2500131
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo