Lyophilization processes are widely employed in the industrial field to preserve several kinds of substances, such as foods and drugs. In some cases, e.g. during the process optimization, the real-time measurement of mass and temperature is important to monitor drying rate and to prevent product damages because of unsuitable temperatures. In these cases sensors and measurement instruments have to be installed inside the vacuum chamber of the freeze dryer, where temperature and pressure can reach -60degC and 1 Pa respectively. This paper deals with the problems related to the measurement of mass and temperature inside freeze dryers and describes a measurement system that has been specifically designed to monitor lyophilization processes.

A Measurement System for Lyophilization Process Monitoring / Vallan, Alberto. - STAMPA. - 1:(2007), pp. 1-5. ((Intervento presentato al convegno Instrumentation and Measurement Technology Conference, 2007. IMTC 2007. IEEE tenutosi a Warsaw, Poland nel 1-3 maggio 2007 [10.1109/IMTC.2007.379000].

A Measurement System for Lyophilization Process Monitoring

VALLAN, Alberto
2007

Abstract

Lyophilization processes are widely employed in the industrial field to preserve several kinds of substances, such as foods and drugs. In some cases, e.g. during the process optimization, the real-time measurement of mass and temperature is important to monitor drying rate and to prevent product damages because of unsuitable temperatures. In these cases sensors and measurement instruments have to be installed inside the vacuum chamber of the freeze dryer, where temperature and pressure can reach -60degC and 1 Pa respectively. This paper deals with the problems related to the measurement of mass and temperature inside freeze dryers and describes a measurement system that has been specifically designed to monitor lyophilization processes.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11583/1841675
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