Lowering in nutrient local availability and rising in host mechanical rigidity are two distinct boundary conditions that affect the growth of solid a-vascular cancers in similar ways (inhibition of growth). In silico experiments based on a physical-mathematical model can shed light on some of the mechanisms at the basis of these effects and suggest that the self-organizing properties of neoplastic populations are greatly modulated by environmental restrictions.

Environmental physical modulation of intrinsic tendency to growth of Multicellular Tumour Spheroids: in silico experiments / M., Griffa; Scalerandi, Marco. - T118:(2005), pp. 183-186. (Intervento presentato al convegno 1st International Meeting on Applied Physics (APHYS-2003) tenutosi a Badajoz (ESP) nel 13–18 Oct. 2003) [10.1238/Physica.Topical.118a00183].

Environmental physical modulation of intrinsic tendency to growth of Multicellular Tumour Spheroids: in silico experiments

SCALERANDI, MARCO
2005

Abstract

Lowering in nutrient local availability and rising in host mechanical rigidity are two distinct boundary conditions that affect the growth of solid a-vascular cancers in similar ways (inhibition of growth). In silico experiments based on a physical-mathematical model can shed light on some of the mechanisms at the basis of these effects and suggest that the self-organizing properties of neoplastic populations are greatly modulated by environmental restrictions.
2005
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/1405593
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