Archivio Istituzionale della RicercaMost acute coronary syndromes (ACS) originate from coronary plaques that are angiographically mild and not flow limiting. These lesions, often characterised by thin-cap fibroatheroma, large lipid cores and macrophage infiltration, are termed ‘vulnerable plaques’ and are associated with a heightened risk of future major adverse cardiovascular events (MACE). However, current imaging modalities lack robust predictive power, and treatment strategies for such plaques remain controversial.
Adverse cardiovascular events in coronary Plaques not undeRgoing pErcutaneous coronary intervention evaluateD with optIcal Coherence Tomography. The PREDICT-AI risk model / Bruno, Francesco; Immobile Molaro, Maddalena; Sperti, Michela; Bianchini, Francesco; Chu, Miao; Cardaci, Camilla; Wańha, Wojciech; Gasior, Pawel; Zecchino, Simone; Pavani, Marco; Vergallo, Rocco; Biscaglia, Simone; Cerrato, Enrico; Gabrio Secco, Gioel; Mennuni, Marco; Mancone, Massimo; De Filippo, Ovidio; Mattesini, Alessio; Canova, Paolo; Boi, Alberto; Ugo, Fabrizio; Scarsini, Roberto; Costa, Francesco; Fabris, Enrico; Campo, Gianluca; Wojakowski, Wojtek; Morbiducci, Umberto; Deriu, Marco; Tu, Shengxian; Piccolo, Raffaele; D'Ascenzo, Fabrizio; Chiastra, Claudio; Burzotta, Francesco. - In: OPEN HEART. - ISSN 2053-3624. - 12:2(2025), pp. 1-7. [10.1136/openhrt-2025-003389]
Adverse cardiovascular events in coronary Plaques not undeRgoing pErcutaneous coronary intervention evaluateD with optIcal Coherence Tomography. The PREDICT-AI risk model.
Michela Sperti;Camilla Cardaci;Marco Pavani;Umberto Morbiducci;Marco Deriu;Fabrizio D'Ascenzo;Claudio Chiastra;
2025
Abstract
Most acute coronary syndromes (ACS) originate from coronary plaques that are angiographically mild and not flow limiting. These lesions, often characterised by thin-cap fibroatheroma, large lipid cores and macrophage infiltration, are termed ‘vulnerable plaques’ and are associated with a heightened risk of future major adverse cardiovascular events (MACE). However, current imaging modalities lack robust predictive power, and treatment strategies for such plaques remain controversial.
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https://hdl.handle.net/11583/3003540