Background: Inflammation is caused by an excess of Sodium ions inside the cell. This generates a variation in the cell's membrane electric potential, becoming a steady state from a thermodynamic viewpoint. Methods: This paper introduces a thermodynamic approach to inflammation based on the fundamental role of the electric potential of the cell membrane, introducing an analysis of the effect of heat transfer related to the inflammation condition. Results: The direct proportionality between the reduction in temperature and the increase of Sodium outflow may ameliorate the inflammation cascade. Conclusions: Based on these ion fluxes, we suggest the consideration of a companion electromagnetic therapeutic wave concept in support of the present anti-inflammatory treatment.
Thermophysical Insights into the Anti-Inflammatory Potential of Magnetic Fields / Lucia, Umberto; Grisolia, Giulia; Ponzetto, Antonio; Deisboeck, Thomas S.. - In: BIOMEDICINES. - ISSN 2227-9059. - ELETTRONICO. - 12:11(2024), pp. 1-11. [10.3390/biomedicines12112534]
Thermophysical Insights into the Anti-Inflammatory Potential of Magnetic Fields
Lucia, Umberto;Grisolia, Giulia;
2024
Abstract
Background: Inflammation is caused by an excess of Sodium ions inside the cell. This generates a variation in the cell's membrane electric potential, becoming a steady state from a thermodynamic viewpoint. Methods: This paper introduces a thermodynamic approach to inflammation based on the fundamental role of the electric potential of the cell membrane, introducing an analysis of the effect of heat transfer related to the inflammation condition. Results: The direct proportionality between the reduction in temperature and the increase of Sodium outflow may ameliorate the inflammation cascade. Conclusions: Based on these ion fluxes, we suggest the consideration of a companion electromagnetic therapeutic wave concept in support of the present anti-inflammatory treatment.File | Dimensione | Formato | |
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https://hdl.handle.net/11583/2994271