Archivio Istituzionale della RicercaCytokine-induced killer (CIK) cells are T lymphocytes expanded ex vivo that are endowed with MHC-independent tumoricidal activity. We have recently demonstrated, in a preclinical setting, that CIK cells are active against autologous bone and soft tissue sarcomas. In particular, CIK cells killed a putative sarcoma stem cell population that may underlie disease relapse and chemoresistance. © 2014 Landes Bioscience.
Activity of cytokine-induced killer cells against bone and soft tissue sarcoma / Sangiolo, D.; Mesiano, G.; Gammaitoni, L.; Aglietta, M.; Grignani, G.. - In: ONCOIMMUNOLOGY. - ISSN 2162-4011. - 3:3(2014). [10.4161/onci.28269]
Activity of cytokine-induced killer cells against bone and soft tissue sarcoma
Mesiano G.;Grignani G.
2014
Abstract
Cytokine-induced killer (CIK) cells are T lymphocytes expanded ex vivo that are endowed with MHC-independent tumoricidal activity. We have recently demonstrated, in a preclinical setting, that CIK cells are active against autologous bone and soft tissue sarcomas. In particular, CIK cells killed a putative sarcoma stem cell population that may underlie disease relapse and chemoresistance. © 2014 Landes Bioscience.
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https://hdl.handle.net/11583/2992533