In this new study, we present an intriguing development in the field of theranostics: the simplistic self-assembly of red-emissive amphiphilic porphyrin-like carbon dots (P-CDs). By harnessing their exceptional photophysical properties, we have revealed a strong candidate as the ideal photosensitizer (PS) for applications, particularly in the realm of imaging. Spanning a remarkable size average between 1–4 nm, these particles exhibit both highly stable and unparalleled emission characteristics between 650 and 715 nm in water in comparison to current carbon dots (CDs) available. Lastly, these CDs were fairly non-toxic when tested against normal human cell lines as well as were found to have favorable imaging capabilities in zebrafish embryo.
The art of simplicity: Water-soluble porphyrin-like carbon dots self-assemble into mesmerizing red glow / Domena, J. B.; Ferreira, B. C. L. B.; Chen, J.; Bartoli, M.; Tagliaferro, A.; Vanni, S.; Graham, R. M.; Leblanc, R. M.. - In: COLLOIDS AND SURFACES. B, BIOINTERFACES. - ISSN 0927-7765. - 234:(2024), pp. 1-10. [10.1016/j.colsurfb.2023.113719]
The art of simplicity: Water-soluble porphyrin-like carbon dots self-assemble into mesmerizing red glow
Bartoli M.;Tagliaferro A.;
2024
Abstract
In this new study, we present an intriguing development in the field of theranostics: the simplistic self-assembly of red-emissive amphiphilic porphyrin-like carbon dots (P-CDs). By harnessing their exceptional photophysical properties, we have revealed a strong candidate as the ideal photosensitizer (PS) for applications, particularly in the realm of imaging. Spanning a remarkable size average between 1–4 nm, these particles exhibit both highly stable and unparalleled emission characteristics between 650 and 715 nm in water in comparison to current carbon dots (CDs) available. Lastly, these CDs were fairly non-toxic when tested against normal human cell lines as well as were found to have favorable imaging capabilities in zebrafish embryo.File | Dimensione | Formato | |
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https://hdl.handle.net/11583/2990638