This study explores the feasibility of bioactive glass scaffolds by using a stereolithographic technology (digital light processing-based vat photopolymerization) as fabrication method and the micro-tomographic reconstruction of an open-cell polymeric sponge as input virtual model to the printing system, in the attempt to replicate the trabecular architecture of cancellous bone. Additively-manufactured scaffolds were investigated from morphological (scanning electron microscopy), microstructural (X-ray diffraction), mechanical (compressive tests) and bioactive viewpoints (immersion studies in simulated body fluid (SBF)). Well-densified foam-like glass scaffolds were obtained after sintering, provided with suitable mechanical properties (compressive strength 21.9 ± 6.2 MPa, elastic modulus 4.8 ± 0.1 GPa, Weibull modulus 3.9) for bone-contact applications. The formation of a hydroxyapatite layer on scaffold struts after soaking in SBF also demonstrated the in vitro bioactivity of the printed structures.

Making foam-like bioactive glass scaffolds by vat photopolymerization / Baino, F.; Dias, J.; Alidoost, M.; Schwentenwein, M.; Verne', E.. - In: OPEN CERAMICS. - ISSN 2666-5395. - ELETTRONICO. - 15:(2023). [10.1016/j.oceram.2023.100392]

Making foam-like bioactive glass scaffolds by vat photopolymerization

Baino F.;Alidoost M.;Verne' E.
2023

Abstract

This study explores the feasibility of bioactive glass scaffolds by using a stereolithographic technology (digital light processing-based vat photopolymerization) as fabrication method and the micro-tomographic reconstruction of an open-cell polymeric sponge as input virtual model to the printing system, in the attempt to replicate the trabecular architecture of cancellous bone. Additively-manufactured scaffolds were investigated from morphological (scanning electron microscopy), microstructural (X-ray diffraction), mechanical (compressive tests) and bioactive viewpoints (immersion studies in simulated body fluid (SBF)). Well-densified foam-like glass scaffolds were obtained after sintering, provided with suitable mechanical properties (compressive strength 21.9 ± 6.2 MPa, elastic modulus 4.8 ± 0.1 GPa, Weibull modulus 3.9) for bone-contact applications. The formation of a hydroxyapatite layer on scaffold struts after soaking in SBF also demonstrated the in vitro bioactivity of the printed structures.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2985169