Objective. To evaluate the reliability and validity of the Italian version of the Brief Questionnaire of Olfactory Disorders (Brief-IT-QOD). Methods. The study consisted of six phases: item generation, reliability analysis (112 dysosmic patients for internal consistency analysis and 61 for test-retest reliability analysis), normative data generation (303 normosmic subjects), validity analysis (comparison of Brief-IT-QOD scores of healthy and dysosmic subjects and scores correlation with psychophysical olfactory testing TDI and SNOT-22 scores), responsiveness analysis (10 dysosmic chronic rhinosinusitis with nasal polyps patients before and after biologic therapy), and cutoff value determination (ROC curve analysis of Brief-IT-QOD sensitivity and specificity). Results. All subjects completed the Brief-IT-QOD. Internal consistency (& alpha; > 0.70) and test-retest reliability (ICC > 0.7) were acceptable and satisfactory for both questionnaire subscales. A significant difference between dysosmic and control subjects was found in both subscales (p < 0.05). Significant correlations between subscales scores and TDI and SNOT-22 scores were observed. Brief-IT-QOD scores before treatment were significantly higher than after biological therapy. Conclusions. Brief-IT-QOD is reliable, valid, responsive to changes in QoL, and recommended for clinical practice and outcome research.

Italian version of the Brief Questionnaire of Olfactory Disorders (Brief-IT-QOD) / Cardella, Arianna; Riva, Giuseppe; Preti, Andrea; Albera, Andrea; Luzi, Livio; Albera, Roberto; Cadei, Davide; Motatto, Gian Marco; Omenetti, Filippo; Pecorari, Giancarlo; Ottaviani, Francesco; Mozzanica, Francesco. - In: ACTA OTORHINOLARYNGOLOGICA ITALICA. - ISSN 0392-100X. - 43:4(2023), pp. 252-261. [10.14639/0392-100X-N2212]

Italian version of the Brief Questionnaire of Olfactory Disorders (Brief-IT-QOD)

Albera, Andrea;
2023

Abstract

Objective. To evaluate the reliability and validity of the Italian version of the Brief Questionnaire of Olfactory Disorders (Brief-IT-QOD). Methods. The study consisted of six phases: item generation, reliability analysis (112 dysosmic patients for internal consistency analysis and 61 for test-retest reliability analysis), normative data generation (303 normosmic subjects), validity analysis (comparison of Brief-IT-QOD scores of healthy and dysosmic subjects and scores correlation with psychophysical olfactory testing TDI and SNOT-22 scores), responsiveness analysis (10 dysosmic chronic rhinosinusitis with nasal polyps patients before and after biologic therapy), and cutoff value determination (ROC curve analysis of Brief-IT-QOD sensitivity and specificity). Results. All subjects completed the Brief-IT-QOD. Internal consistency (& alpha; > 0.70) and test-retest reliability (ICC > 0.7) were acceptable and satisfactory for both questionnaire subscales. A significant difference between dysosmic and control subjects was found in both subscales (p < 0.05). Significant correlations between subscales scores and TDI and SNOT-22 scores were observed. Brief-IT-QOD scores before treatment were significantly higher than after biological therapy. Conclusions. Brief-IT-QOD is reliable, valid, responsive to changes in QoL, and recommended for clinical practice and outcome research.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2982349