Wall shear stress (WSS) is involved in coronary artery plaque pathological mechanisms and modulation of gene expression. This study aims to provide a comprehensive haemodynamic and biological description of unstable (intact-fibrous-cap, IFC, and ruptured-fibrous-cap, RFC) and stable (chronic coronary syndrome, CCS) plaques and investigate any correlation between WSS and molecular pathways.

Coronary artery plaque rupture and erosion: Role of wall shear stress profiling and biological patterns in acute coronary syndromes / Russo, G., Pedicino, D., Chiastra, C., Vinci, R., Rizzini, M.L., Genuardi, L., Sarraf, M., D'Aiello, A., Bologna, M., Aurigemma, C., Bonanni, A., Bellantoni, A., D'Ascenzo, F., Ciampi, P., Zambrano, A., Mainardi, L., Ponzo, M., Severino, A., Trani, C., Massetti, M., et al.. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - 370:(2023), pp. 356-365. [10.1016/j.ijcard.2022.10.139]

Coronary artery plaque rupture and erosion: Role of wall shear stress profiling and biological patterns in acute coronary syndromes

Chiastra, Claudio;Rizzini, Maurizio Lodi;Gallo, Diego;Morbiducci, Umberto;
2023

Abstract

Wall shear stress (WSS) is involved in coronary artery plaque pathological mechanisms and modulation of gene expression. This study aims to provide a comprehensive haemodynamic and biological description of unstable (intact-fibrous-cap, IFC, and ruptured-fibrous-cap, RFC) and stable (chronic coronary syndrome, CCS) plaques and investigate any correlation between WSS and molecular pathways.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2972978