Wall shear stress (WSS) is involved in coronary artery plaque pathological mechanisms and modulation of gene expression. This study aims to provide a comprehensive haemodynamic and biological description of unstable (intact-fibrous-cap, IFC, and ruptured-fibrous-cap, RFC) and stable (chronic coronary syndrome, CCS) plaques and investigate any correlation between WSS and molecular pathways.

Coronary artery plaque rupture and erosion: Role of wall shear stress profiling and biological patterns in acute coronary syndromes / Russo, Giulio; Pedicino, Daniela; Chiastra, Claudio; Vinci, Ramona; Rizzini, Maurizio Lodi; Genuardi, Lorenzo; Sarraf, Mohammad; D'Aiello, Alessia; Bologna, Marco; Aurigemma, Cristina; Bonanni, Alice; Bellantoni, Antonio; D'Ascenzo, Fabrizio; Ciampi, Pellegrino; Zambrano, Aniello; Mainardi, Luca; Ponzo, Myriana; Severino, Anna; Trani, Carlo; Massetti, Massimo; Gallo, Diego; Migliavacca, Francesco; Maisano, Francesco; Lerman, Amir; Morbiducci, Umberto; Burzotta, Francesco; Crea, Filippo; Liuzzo, Giovanna. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - (2022). [10.1016/j.ijcard.2022.10.139]

Coronary artery plaque rupture and erosion: Role of wall shear stress profiling and biological patterns in acute coronary syndromes

Chiastra, Claudio;Rizzini, Maurizio Lodi;Gallo, Diego;Morbiducci, Umberto;
2022

Abstract

Wall shear stress (WSS) is involved in coronary artery plaque pathological mechanisms and modulation of gene expression. This study aims to provide a comprehensive haemodynamic and biological description of unstable (intact-fibrous-cap, IFC, and ruptured-fibrous-cap, RFC) and stable (chronic coronary syndrome, CCS) plaques and investigate any correlation between WSS and molecular pathways.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2972978
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