Structural and functional arterial properties commonly impair with aging process. These effects on vasculature could act at many levels from microcirculation to large vessels. Above normal aging process classic cardio-vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, etc.) accelerate the physiological process leading to premature structural and functional alterations that has also been termed early vascular aging. Target organ damage evaluation could be clinically important since these alterations precede by many years' cardiovascular events and so their assessment can predict the onset of more serious and costly events giving the opportunity to prevent CV events by earlier therapeutic intervention. This review will focus on large artery functional properties and particularly on the role of inflammation on the aortic stiffening process.

Vascular Aging and Disease of the Large Vessels: Role of Inflammation / Maloberti, Alessandro; Vallerio, Paola; Triglione, Nicola; Occhi, Lucia; Panzeri, Francesco; Bassi, Ilaria; Pansera, Francesco; Piccinelli, Enrico; Peretti, Alessio; Garatti, Laura; Palazzini, Matteo; Sun, Jinwei; Grasso, Enzo; Giannattasio, Cristina. - In: HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION. - ISSN 1120-9879. - 26:3(2019), pp. 175-182. [10.1007/s40292-019-00318-4]

Vascular Aging and Disease of the Large Vessels: Role of Inflammation

Piccinelli, Enrico;
2019

Abstract

Structural and functional arterial properties commonly impair with aging process. These effects on vasculature could act at many levels from microcirculation to large vessels. Above normal aging process classic cardio-vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, etc.) accelerate the physiological process leading to premature structural and functional alterations that has also been termed early vascular aging. Target organ damage evaluation could be clinically important since these alterations precede by many years' cardiovascular events and so their assessment can predict the onset of more serious and costly events giving the opportunity to prevent CV events by earlier therapeutic intervention. This review will focus on large artery functional properties and particularly on the role of inflammation on the aortic stiffening process.
File in questo prodotto:
File Dimensione Formato  
2019 - Vascular Aging and Disease of the Large Vessels Role of Infammation.pdf

non disponibili

Tipologia: 2a Post-print versione editoriale / Version of Record
Licenza: Non Pubblico - Accesso privato/ristretto
Dimensione 892.63 kB
Formato Adobe PDF
892.63 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2970579