Archivio Istituzionale della RicercaCancer results from dysregulation of multiple steps of gene expression programs. We review how transcriptome profiling has been widely explored for cancer classification and biomarker discovery but resulted in limited clinical impact. Therefore, we discuss alternative and complementary omics approaches.
Molecular portraits: the evolution of the concept of transcriptome-based cancer signatures / Modelska, A; Quattrone, A; Re, A. - In: BRIEFINGS IN BIOINFORMATICS. - ISSN 1477-4054. - ELETTRONICO. - 16:6(2015), pp. 1000-1007. [10.1093/bib/bbv013]
Molecular portraits: the evolution of the concept of transcriptome-based cancer signatures.
Re A
2015
Abstract
Cancer results from dysregulation of multiple steps of gene expression programs. We review how transcriptome profiling has been widely explored for cancer classification and biomarker discovery but resulted in limited clinical impact. Therefore, we discuss alternative and complementary omics approaches.
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Molecular Portraits The Evolution of the Concept of Transcriptome-bassed Cancer Signatures Brief. in Bioinform 2015.pdf
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Utilizza questo identificativo per citare o creare un link a questo documento:
https://hdl.handle.net/11583/2970531