Recent and rapid progression in three-dimensional (3D) printing techniques has revolutionized conventional therapies in medicine; 3D printed constructs are gradually being recognized as common substitutes for the replacement of skin wounds. As gel-inks, large numbers of natural and synthetic (e.g., collagen and polyurethane, respectively) substances were used to be printed into different shapes and sizes for managing both acute and chronic skin wounds. The resultant 3D printed scaffolds not only provide physical support but also act as supporting niches for improving immunomodulation and vascularization and subsequent accelerated wound healing. Recently, the use of thermosensitive and pH-responsive gels has made it possible to prepare 3D printed constructs with the ability to facilitate in situ crosslinking within the biopolymer and with native wound edge tissue as well as to fill the exact shape of wound damage. In this chapter, we aim to introduce the current state of 3D printable gel-inks utilized for skin wound treatment and illustrate future prospects in this amazing area of science.

Three Dimensional (3D) Printable Gel-Inks for Skin Tissue Regeneration / Nazarnezhad, ; Hooshmand, S.; Baino, F.; Kargozar, S. - In: 3D printable Gel-inks for Tissue Engineering Chemistry, Processing, and Applications / A. Kumar, S.I. Voicu, V. Kumar Thakur. - ELETTRONICO. - Singapore : Springer, 2021. - ISBN 978-981-16-4666-9. - pp. 191-227 [10.1007/978-981-16-4667-6_6]

Three Dimensional (3D) Printable Gel-Inks for Skin Tissue Regeneration

Baino, F.;
2021

Abstract

Recent and rapid progression in three-dimensional (3D) printing techniques has revolutionized conventional therapies in medicine; 3D printed constructs are gradually being recognized as common substitutes for the replacement of skin wounds. As gel-inks, large numbers of natural and synthetic (e.g., collagen and polyurethane, respectively) substances were used to be printed into different shapes and sizes for managing both acute and chronic skin wounds. The resultant 3D printed scaffolds not only provide physical support but also act as supporting niches for improving immunomodulation and vascularization and subsequent accelerated wound healing. Recently, the use of thermosensitive and pH-responsive gels has made it possible to prepare 3D printed constructs with the ability to facilitate in situ crosslinking within the biopolymer and with native wound edge tissue as well as to fill the exact shape of wound damage. In this chapter, we aim to introduce the current state of 3D printable gel-inks utilized for skin wound treatment and illustrate future prospects in this amazing area of science.
2021
978-981-16-4666-9
978-981-16-4667-6
3D printable Gel-inks for Tissue Engineering Chemistry, Processing, and Applications
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2937572