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EnglishRecently developed calcium-phosphate glass formulations are proposed in this chapter as a new class of materials for biomedical optics and photonics. The glasses have been designed and carefully prepared in our laboratory to be dissolvable in biological fluids while being optically transparent, mechan-ically reliable both in dry and humid environments, and suitable for both preform extrusion and fiber drawing. Optical fibers have been drawn from these glasses using our custom-made induction heated drawing tower and showed attenuation loss values from one to two orders of magnitude lower than the counterpart polymeric-based bioresorbable devices reported in liter-ature. In addition, the optical fibers have been implanted in living rats for several weeks and no clinical signs of any adverse effect have been found. Results on the inscription and characterization of different types of fiber Bragg grating-based optical filters will be also shown, together with the demonstration of the suitability of the above-mentioned bioresorbable opti-cal fibers for time-domain diffuse optical spectroscopy.
Optical Quality Resorbable Calcium-Phosphate Glasses for Biophotonic Applications / Pugliese, Diego; Boetti, Nadia Giovanna; Janner, Davide; Milanese, Daniel. - ELETTRONICO. - (2021), pp. 229-252. [10.1007/978-3-030-85776-9_7]
| Titolo: | Optical Quality Resorbable Calcium-Phosphate Glasses for Biophotonic Applications | |
| Autori: | ||
| Data di pubblicazione: | 2021 | |
| Titolo del libro: | Ceramics, Glass and Glass-Ceramics From Early Manufacturing Steps Towards Modern Frontiers | |
| Serie: | ||
| Abstract: | Recently developed calcium-phosphate glass formulations are proposed in this chapter as a new cla...ss of materials for biomedical optics and photonics. The glasses have been designed and carefully prepared in our laboratory to be dissolvable in biological fluids while being optically transparent, mechan-ically reliable both in dry and humid environments, and suitable for both preform extrusion and fiber drawing. Optical fibers have been drawn from these glasses using our custom-made induction heated drawing tower and showed attenuation loss values from one to two orders of magnitude lower than the counterpart polymeric-based bioresorbable devices reported in liter-ature. In addition, the optical fibers have been implanted in living rats for several weeks and no clinical signs of any adverse effect have been found. Results on the inscription and characterization of different types of fiber Bragg grating-based optical filters will be also shown, together with the demonstration of the suitability of the above-mentioned bioresorbable opti-cal fibers for time-domain diffuse optical spectroscopy. | |
| ISBN: | 978-3-030-85775-2 978-3-030-85776-9 | |
| Appare nelle tipologie: | 2.1 Contributo in volume (Capitolo o Saggio) |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| Pre-print autore.pdf | Pre-print | 1. Preprint / submitted version [pre- review] | PUBBLICO - Tutti i diritti riservati | Administrator Richiedi una copia |
| Post-print autore.pdf | Post-print autore | 2. Post-print / Author's Accepted Manuscript | PUBBLICO - Tutti i diritti riservati | Embargo: 23/10/2022 Richiedi una copia |
| Optical Quality Resorbable Calcium-Phosphate Glasses for Biophotonic Applications.pdf | Post-print editoriale | 2a Post-print versione editoriale / Version of Record | Non Pubblico - Accesso privato/ristretto | Administrator Richiedi una copia |
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