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EnglishSome special implantable materials are defined as “bioactive” if they can bond to living bone, forming a tight and chemically‐stable interface. This property, which is inherent to some glass compositions, or can be induced by applying appropriate surface treatments on otherwise bio‐inert metals, can be evaluated in vitro by immersion studies in simulated body fluid (SBF), mimicking the composition of human plasma. As a result, apatite coating may form on the material surface, and the presence of this bone‐like “biomimetic skin” is considered predictive of bone‐bonding ability in vivo. This review article summarizes the story and evolution of in vitro bioactivity testing methods using SBF, highlighting the influence of testing parameters (e.g., formulation and circulation of the solution) and material‐related parameters (e.g., composition, geometry, texture). Suggestions for future methodological refinements are also provided at the end of the paper.
The use of simulated body fluid (SBF) for assessing materials bioactivity in the context of tissue engineering: Review and challenges / Baino, F.; Yamaguchi, S.. - In: BIOMIMETICS. - ISSN 2313-7673. - ELETTRONICO. - 5:4(2020), p. 57.
| Titolo: | The use of simulated body fluid (SBF) for assessing materials bioactivity in the context of tissue engineering: Review and challenges | |
| Autori: | ||
| Data di pubblicazione: | 2020 | |
| Rivista: | ||
| Digital Object Identifier (DOI): | http://dx.doi.org/10.3390/biomimetics5040057 | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| Review SBF-biomaterials_Biomimetics 2020.pdf | 2a Post-print versione editoriale / Version of Record |  | Visibile a tuttiVisualizza/Apri |
http://hdl.handle.net/11583/2903316
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