Why does thermomagnetic resonance affect cancer growth? A non-equilibrium thermophysical approach

theoretically [1,2] and experimentally [3-5]. It has been explained by an equilibrium thermodynamic approach, but two related open problems can be highlighted: (i) Does there exist a magnetic interaction or do there exist any other processes? (ii) Do there exist also thermal effects? Here, we introduce a non-equilibrium thermodynamic approach to respond to these questions. The results obtained point out that: (iii) The effect produced by the electromagnetic wave is just a consequence of the magnetic interaction; (iv) The interaction of the electromagnetic wave causes also thermal effects, even if there have been applied low frequency electromagnetic waves; (v) The presence of the magnetic field generates a symmetry breaking in the Onsager's coefficients with a related perturbation of the stationary state of the cancer. Bibliography [1] Lucia U., Grisolia G. Resonance in Thermal Fluxes Through Cancer Membrane. Atti dell’Accademia Peloritana dei Pericolanti, 2020, 98, SC1-SC6, DOI 10.1478/AAPP.981SC1. [2] Lucia U., Grisolia G. Second law efficiency for living cells, Frontiers in Bioscience 2017, 9, 270- 275, DOI 10.2741/s487. [3] Lucia U., Grisolia G., Ponzetto A., Bergandi L., Silvagno F. Thermomagnetic resonance affects cancer growth and motility, R. Soc. Open Sci. 2020, 7, 200299, DOI 10.1098/rsos.200299. [4] Bergandi L., Lucia U., Grisolia G., Granata R., Gesmundo I., Ponzetto A., Paolucci E., Borchiellini R., Ghigo E., Silvagno F. The extremely low frequency electromagnetic stimulation selective for cancer cells elicits growth arrest through a metabolic shift, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2019, 1866, 1389-1397, DOI 10.1016/j.bbamcr.2019.05.006. [5] Lucia U., Grazzini G., Montrucchio B., Grisolia G., Borchiellini R., Gervino G., Castagnoli C., Ponzetto A., Silvagno F. Constructal thermodynamics combined with infrared experiments to evaluate temperature differences in cells, Sci. Rep. 2015, 5, 11587, DOI 10.1038/srep11587.