Slow biphasic complexes (SBC) have been identified in the EEG of patients suffering for inflammatory brain diseases. Their amplitude, location and frequency of appearance were found to correlate with the severity of encephalitis. Other characteristics of SBCs and of EEG traces of patients could reflect the grade of pathology. Here, EEG rhythms are investigated together with SBCs for a better characterization of encephalitis. EEGs have been acquired from pediatric patients: ten controls and ten encephalitic patients. They were split by neurologists into five classes of different severity of the pathology. The relative power of EEG rhythms was found to change significantly in EEGs labeled with different severity scores. Moreover, a significant variation was found in the last seconds before the appearance of an SBC. This information and quantitative indexes characterizing the SBCs were used to build a binary classification decision tree able to identify the classes of severity. True classification rate of the best model was 76.1% (73.5% with leave-one-out test). Moreover, the classification errors were among classes with similar severity scores (precision higher than 80% was achieved considering three instead of five classes). Our classification method may be a promising supporting tool for clinicians to diagnose, assess and make the follow-up of patients with encephalitis.
Automated diagnosis of encephalitis in pediatric patients using EEG rhythms and slow biphasic complexes / Mesin, L.; Valerio, M.; Capizzi, G.. - In: AUSTRALASIAN PHYSICAL & ENGINEERING SCIENCES IN MEDICINE. - ISSN 0158-9938. - (2020).
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|Titolo:||Automated diagnosis of encephalitis in pediatric patients using EEG rhythms and slow biphasic complexes|
|Data di pubblicazione:||2020|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1007/s13246-020-00893-0|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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