Smartphone-based estimation of item 3.8 of the MDS-UPDRS-III for assessing leg agility in people with Parkinson’s disease”

Borzi', Luigi; Varrecchia, Marilena; Stefano, Sibille; Olmo, Gabriella; Carlo Alberto Artusi,; Margherita, Fabbri; Mario Giorgio Rizzone,; Alberto, Romagnolo; Maurizio, Zibetti; Leonardo, Lopiano

doi:10.1109/OJEMB.2020.2993463

In this paper we investigated the use of smartphone sensors and Artiﬁcial Intelligence techniques for the automatic quantiﬁcation of the MDS-UPDRS-Part III Leg Agility (LA) task, representative of lower limb bradykinesia. Methods: We collected inertial data from 93 PD subjects. Four expert neurologists provided clinical evaluations. We employed a novel Artiﬁcial Neural Network approach in order to get a continuous output, going beyond the MDS-UPDRS score discretization. Results: We found a Pearson correlation of 0.92 between algorithm output and average clinical score, compared to an inter-rater agreement index of 0.88. Furthermore, the classiﬁcation error was less than 0.5 scale point in about 80% cases.Conclusions:Weproposedanobjectiveandreliabletoolfor theautomaticquantiﬁcationoftheMDS-UPDRSLegAgilitytask. In perspective, this tool is part of a larger monitoring program to be carried out during activities of daily living, and managed by the patients themselves.

Smartphone-based estimation of item 3.8 of the MDS-UPDRS-III for assessing leg agility in people with Parkinson’s disease” / Borzi', Luigi; Varrecchia, Marilena; Sibille, Stefano; Olmo, Gabriella; Alberto Artusi, Carlo; Fabbri, Margherita; Giorgio Rizzone, Mario; Romagnolo, Alberto; Zibetti, Maurizio; Lopiano, Leonardo. - In: IEEE OPEN JOURNAL OF ENGINEERING IN MEDICINE AND BIOLOGY. - ISSN 2644-1276. - ELETTRONICO. - 1(2020), pp. 140-147.

Titolo:	Smartphone-based estimation of item 3.8 of the MDS-UPDRS-III for assessing leg agility in people with Parkinson’s disease”
Autori:	BORZI', LUIGI VARRECCHIA, MARILENA Stefano Sibille OLMO, Gabriella Carlo Alberto Artusi Margherita Fabbri Mario Giorgio Rizzone Alberto Romagnolo Maurizio Zibetti Leonardo Lopiano mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2020
Rivista:	IEEE OPEN JOURNAL OF ENGINEERING IN MEDICINE AND BIOLOGY
Digital Object Identifier (DOI):	http://dx.doi.org/10.1109/OJEMB.2020.2993463
Appare nelle tipologie:	1.1 Articolo in rivista

File in questo prodotto:

File	Descrizione	Tipologia	Licenza
09090332.pdf		2a Post-print versione editoriale / Version of Record		Visibile a tuttiVisualizza/Apri

Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11583/2831832

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

PORTO @ Archivio Istituzionale della Ricerca

File in questo prodotto: