Calcium carbonate nanoparticles (CaCO3NPs) derived from CO2 are promising materials for different industrial applications. It is imperative to understand their toxicological profile in biological systems as the human and environmental exposures to CaCO3NPs increases with growing production. Here, we analyse the cytotoxicity of CaCO3NPs synthesized from a CaO slurry on two cell lines, and in vivo on zebrafish (Danio Rerio). Our results demonstrate the CaCO3NPs in vitro safety as they do not cause cell death or genotoxicity. Moreover, zebrafish treated with CaCO3NPs develop without any abnormalities, confirming the safety and biocompatibility of this nanomaterial.
Toxicological profile of calcium carbonate nanoparticles for industrial applications / d'Amora, M.; Liendo, F.; Deorsola, F. A.; Bensaid, S.; Giordani, S.. - In: COLLOIDS AND SURFACES. B, BIOINTERFACES. - ISSN 0927-7765. - 190(2020), p. 110947. [10.1016/j.colsurfb.2020.110947]
Titolo: | Toxicological profile of calcium carbonate nanoparticles for industrial applications | |
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Data di pubblicazione: | 2020 | |
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Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.colsurfb.2020.110947 | |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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1-s2.0-S0927776520301776-main.pdf | 2a Post-print versione editoriale / Version of Record | ![]() | Visibile a tuttiVisualizza/Apri |
http://hdl.handle.net/11583/2830738