Scaffold pore size plays a fundamental role in the regeneration of new tissue since it has been shown to direct cell activity in situ. It is well known that cellular response changes in relation with pores diameter. Consequently, researchers developed efficient approaches to realize scaffolds with controllable macro-, micro-, and nanoporous architecture. In this context, new strategies aiming at the manufacturing of scaffolds with multiscale pore networks have emerged, in the attempt to mimic the complex hierarchical structures found in living systems. In this review, we aim at providing an overview of the fabrication methods currently adopted to realize scaffolds with controlled, multisized pores highlighting their specific influence on cellular activity.
Reviewing recently developed technologies to direct cell activity through the control of pore size: From the macro- to the nanoscale / Sgarminato, Viola; Tonda-Turo, C.; Ciardelli, G.. - In: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH. PART B, APPLIED BIOMATERIALS.. - ISSN 1552-4973. - (2019), pp. 1-10.
|Titolo:||Reviewing recently developed technologies to direct cell activity through the control of pore size: From the macro- to the nanoscale|
|Data di pubblicazione:||2019|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1002/jbm.b.34467|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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