PORTO @ 
Archivio Istituzionale della Ricerca
IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishStar-shaped poly(ethylene glycol)-N-hydroxysuccinimide (star- PEG-NHS) has shown great promise in a variety of biomedical applications owing to its non-toxicity, innate non-immunogenic properties and versatile, multifunctional end groups. However, its complex and sophisticated synthetic methods, as well as high costs, have significantly impeded its wide application. Here, we report the design and synthesis of a hyperbranched PEG-based polymer with multiple NHS functional groups (>12). The hyper- branched PEG-based multi-NHS polymer can react easily with a protein (bovine serum albumin, BSA) to form a PEG-protein hydro- gel that displays great potential for biomedical applications.
Hyperbranched PEG-based multi-NHS polymer and bioconjugation with BSA / A, Sigen; Xu, Qian; Zhou, Dezhong; Gao, Yongsheng; Vasquez, Jeddah Marie; Greiser, Udo; Wang, Wei; Liu, Wenguang; Wang, Wenxin. - In: POLYMER CHEMISTRY. - ISSN 1759-9954. - ELETTRONICO. - 8:(2017), pp. 1283-1287. [10.1039/C6PY01719C]
| Titolo: | Hyperbranched PEG-based multi-NHS polymer and bioconjugation with BSA | |
| Autori: | ||
| Data di pubblicazione: | 2017 | |
| Rivista: | ||
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1039/C6PY01719C | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
http://hdl.handle.net/11583/2709134
Copyright © 2022