In this paper the first glass based resorbable optical fiber is manufactured and characterized, showing values of attenuation loss from one to two orders of magnitude lower than the polymeric based bioresorbable devices reported in literature. The fiber behaves as a singlemode waveguide at the lower limit of the first biological window (1300 nm) and as a multi-mode waveguide in the visible region (630 nm). Highly transparent calcium-phosphate glasses (PGs) are proposed as a new class of materials for biomedical optics, managing to combine for the first time in a vitreous material solubility in aqueous media, transparency in the near UV region, low intrinsic attenuation loss and thermal stability during fiber drawing. In-vitro tests in physiological conditions show dissolution kinetics of glass fibers in about a month.

Novel biocompatible and resorbable UV-transparent phosphate glass based optical fiber / CECI GINISTRELLI, Edoardo; Pugliese, Diego; Boetti, NADIA GIOVANNA; Novajra, Giorgia; Ambrosone, Annarita; Lousteau, Joris; VITALE BROVARONE, Chiara; Abrate, Silvio; Milanese, Daniel. - In: OPTICAL MATERIALS EXPRESS. - ISSN 2159-3930. - ELETTRONICO. - 6:6(2016), pp. 2040-2051. [10.1364/OME.6.002040]

Novel biocompatible and resorbable UV-transparent phosphate glass based optical fiber

CECI GINISTRELLI, EDOARDO;PUGLIESE, DIEGO;BOETTI, NADIA GIOVANNA;NOVAJRA, GIORGIA;VITALE BROVARONE, CHIARA;MILANESE, DANIEL
2016

Abstract

In this paper the first glass based resorbable optical fiber is manufactured and characterized, showing values of attenuation loss from one to two orders of magnitude lower than the polymeric based bioresorbable devices reported in literature. The fiber behaves as a singlemode waveguide at the lower limit of the first biological window (1300 nm) and as a multi-mode waveguide in the visible region (630 nm). Highly transparent calcium-phosphate glasses (PGs) are proposed as a new class of materials for biomedical optics, managing to combine for the first time in a vitreous material solubility in aqueous media, transparency in the near UV region, low intrinsic attenuation loss and thermal stability during fiber drawing. In-vitro tests in physiological conditions show dissolution kinetics of glass fibers in about a month.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11583/2642917
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