Archivio Istituzionale della RicercaThanks to their impressive catalytic properties, cerium oxide nanoparticles (nanoceria) are able to mimic the activity of superoxide dismutase and of catalase, therefore acting as reactive oxygen species (ROS) scavengers in many biological contexts, for instance offering neuroprotection and reduction of apoptosis rate in many types of cells exposed to oxidative stress (stem cells, endothelial cells, epithelial cells, osteoblasts, etc.).
Transcriptional profile of genes involved in oxidative stress and antioxidant defense in PC12 cells following treatment with cerium oxide nanoparticles / Ciofani, Gianni; Genchi, Giada Graziana; Mazzolai, Barbara; Mattoli, Virgilio. - In: BIOCHIMICA ET BIOPHYSICA ACTA. - ISSN 0006-3002. - 1840:1(2014), pp. 495-506. [10.1016/j.bbagen.2013.10.009]
Transcriptional profile of genes involved in oxidative stress and antioxidant defense in PC12 cells following treatment with cerium oxide nanoparticles
CIOFANI, GIANNI;
2014
Abstract
Thanks to their impressive catalytic properties, cerium oxide nanoparticles (nanoceria) are able to mimic the activity of superoxide dismutase and of catalase, therefore acting as reactive oxygen species (ROS) scavengers in many biological contexts, for instance offering neuroprotection and reduction of apoptosis rate in many types of cells exposed to oxidative stress (stem cells, endothelial cells, epithelial cells, osteoblasts, etc.).
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https://hdl.handle.net/11583/2621389
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