Inert polytetraﬂuoroethylene (PTFE) membranes for periodontal regeneration suffer fromweak osteoconductive properties. In this work, a strategy for hydroxyapatite (HAp) coating onPTFE ﬁlms through an adhesive layer of self-polymerized 3,4-dihydroxy-DL-phenylalanine(polyDOPA) was developed to improve surface properties. Physico-chemical and morpho-logical analysis demonstra ted the deposition of polyDOPA and HAp, with an increase insurface roughness and wettability. A discontinuous coating was present after 14 days in PBS and MC3T3-E1 cells proliferation and adhesion were improved. Results conﬁrmed thepotential application of polyDOPA/HAp-coated ﬁlmsfor periodontal disease treatments.
|Titolo:||PolyDOPA Mussel-Inspired Coating as a Means for Hydroxyapatite Entrapmenton Polytetraﬂuoroethylene Surface forApplication in Periodontal Diseases|
|Data di pubblicazione:||2016|
|Digital Object Identifier (DOI):||10.1002/mabi.201500241|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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