Archivio Istituzionale della RicercaWe review some of the recent progresses made by the application of polymer physics to the understanding of the spatial organization of chromosomes in the cell nucleus. In particular, we focus on some scaling properties of the contact probability of pairs of sites, discovered by recent genome-wide experiments exploiting new technologies such as Hi-C methods.
Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus / M., Barbieri; A., Scialdone; Gamba, ANDREA ANTONIO; A., Pombo; M., Nicodemi. - In: SOFT MATTER. - ISSN 1744-683X. - STAMPA. - 9:(2013), pp. 8631-8635. [10.1039/c3sm51436f]
Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus
GAMBA, ANDREA ANTONIO;
2013
Abstract
We review some of the recent progresses made by the application of polymer physics to the understanding of the spatial organization of chromosomes in the cell nucleus. In particular, we focus on some scaling properties of the contact probability of pairs of sites, discovered by recent genome-wide experiments exploiting new technologies such as Hi-C methods.
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https://hdl.handle.net/11583/2520485
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