Archivio Istituzionale della RicercaOne-step techniques are a promising approach for cartilage repair. This study introduces a simple chondrocyte culturefree approach with autologous cartilage fragments loaded onto a mixed scaffold composed of high molecular weight hyaluronic acid derivative felt (Hyaff-11), injectable human fibrin glue (Tisseel) and autologous platelet-rich plasma (PRP). Nanoindentation of goat samples showed mechanical properties close to native goat-trochelarcartilage.
One stage osteochondral repair with cartilage fragments in a hybrid scaffold: rabbit and goat animal model / Marmotti, A.; Bruzzone, M.; Castoldi, F.; Rossi, R.; Bonasia, D. E.; Cottino, U.; Maiello, A.; Bignardi, Cristina. - In: JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY. - ISSN 1590-9999. - STAMPA. - 12:Suppl.1(2011), p. S161. [10.1007/s10195-011-0151-1]
One stage osteochondral repair with cartilage fragments in a hybrid scaffold: rabbit and goat animal model
BIGNARDI, CRISTINA
2011
Abstract
One-step techniques are a promising approach for cartilage repair. This study introduces a simple chondrocyte culturefree approach with autologous cartilage fragments loaded onto a mixed scaffold composed of high molecular weight hyaluronic acid derivative felt (Hyaff-11), injectable human fibrin glue (Tisseel) and autologous platelet-rich plasma (PRP). Nanoindentation of goat samples showed mechanical properties close to native goat-trochelarcartilage.
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https://hdl.handle.net/11583/2504456
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