A novel fabrication technique, a combination of slurry dipping and electrospraying, was used to produce hydroxyapatite foams as potential matrices for bone tissue engineering applications. In this study, scaffolds that were slurry dipped and electrosprayed for different time intervals were compared with foams prepared by the individual methods of dipping and electrospraying. Significant differences in the distribution of cracks on the struts, the strut thickness and porosity were observed on the sintered foams prepared under the varied conditions. All the sintered structures had average porosities in the range 84–94% and desirable pore interconnections, while the combined method produced foams of uniform pore distribution, thicker struts and improved mechanical properties. Further improvement of the mechanical properties has also been achieved by altering the sintering conditions.
Dipping and electrospraying for the preparation of hydroxyapatite foams for bone tissue engineering / Muthutantri, Ai; Huang, J; Edirisinghe, Mj; Bretcanu, OANA ANCA; Boccaccini, Ar. - In: BIOMEDICAL MATERIALS. - ISSN 1748-6041. - 3:2(2008). [10.1088/1748-6041/3/2/025009]
Dipping and electrospraying for the preparation of hydroxyapatite foams for bone tissue engineering
BRETCANU, OANA ANCA;
2008
Abstract
A novel fabrication technique, a combination of slurry dipping and electrospraying, was used to produce hydroxyapatite foams as potential matrices for bone tissue engineering applications. In this study, scaffolds that were slurry dipped and electrosprayed for different time intervals were compared with foams prepared by the individual methods of dipping and electrospraying. Significant differences in the distribution of cracks on the struts, the strut thickness and porosity were observed on the sintered foams prepared under the varied conditions. All the sintered structures had average porosities in the range 84–94% and desirable pore interconnections, while the combined method produced foams of uniform pore distribution, thicker struts and improved mechanical properties. Further improvement of the mechanical properties has also been achieved by altering the sintering conditions.Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11583/1853732
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo