Advanced bone tissue engineering approaches rely on implanting synthetic grafts for the management of mid to large bone defects in order to overcome the common limitations associated with the use of transplant materials. Bioceramics are especially effective due to their versatile functional properties and processing methods. This chapter provides a picture of ceramic scaffolds for bone tissue engineering, focusing on additive manufacturing technologies and, specifically, the emerging method of digital light processing. The functional and structural complexity of natural bone makes the design of scaffolds a complex challenge as their chemical, structural and functional properties have to meet very specific requirements, e.g. adequate support properties, bone-bonding capability and a macro- and microporous structure to promote cell colonization and vascularization. Many fabrication techniques are currently available for the production of porous artificial biomaterials. Among them, the class of additive manufacturing technologies is one of the most promising methods for the development of mechanically competent and structurally highly defined scaffolds with tailored properties for bone tissue engineering applications.

Additive Manufacturing of Bioceramic Scaffolds for Bone Tissue Regeneration with Emphasis on Stereolithographic Processing / Baino, F.; Fiume, E.; Magnaterra, G.; Verne', E. - In: 3D printable Gel-inks for Tissue Engineering Chemistry, Processing, and Applications / A. Kumar, S.I. Voicu, V. Kumar Thakur. - ELETTRONICO. - Singapore : Springer, 2021. - ISBN 978-981-16-4666-9. - pp. 297-331 [10.1007/978-981-16-4667-6_9]

Additive Manufacturing of Bioceramic Scaffolds for Bone Tissue Regeneration with Emphasis on Stereolithographic Processing

Baino, F.;Fiume, E.;Verne', E.
2021

Abstract

Advanced bone tissue engineering approaches rely on implanting synthetic grafts for the management of mid to large bone defects in order to overcome the common limitations associated with the use of transplant materials. Bioceramics are especially effective due to their versatile functional properties and processing methods. This chapter provides a picture of ceramic scaffolds for bone tissue engineering, focusing on additive manufacturing technologies and, specifically, the emerging method of digital light processing. The functional and structural complexity of natural bone makes the design of scaffolds a complex challenge as their chemical, structural and functional properties have to meet very specific requirements, e.g. adequate support properties, bone-bonding capability and a macro- and microporous structure to promote cell colonization and vascularization. Many fabrication techniques are currently available for the production of porous artificial biomaterials. Among them, the class of additive manufacturing technologies is one of the most promising methods for the development of mechanically competent and structurally highly defined scaffolds with tailored properties for bone tissue engineering applications.
978-981-16-4666-9
978-981-16-4667-6
3D printable Gel-inks for Tissue Engineering Chemistry, Processing, and Applications
File in questo prodotto:
File Dimensione Formato  
Chapter gel-bioceramic-SLA book Springer 2021.pdf

non disponibili

Tipologia: 2a Post-print versione editoriale / Version of Record
Licenza: Non Pubblico - Accesso privato/ristretto
Dimensione 626.42 kB
Formato Adobe PDF
626.42 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Chapter AM ceramic scaffold_final.pdf

Open Access dal 13/09/2022

Tipologia: 2. Post-print / Author's Accepted Manuscript
Licenza: PUBBLICO - Tutti i diritti riservati
Dimensione 1.5 MB
Formato Adobe PDF
1.5 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2937576