Chapter 6 discusses open- and closed-loop control systems applied to freeze-drying processes, evidencing the possibility of model-based approaches for rejection of disturbances, failure prevention, and process optimization. At the end it will be shown how some of the recently developed tools can be useful for automatic cycle development. All three steps of the process, namely freezing, primary drying, and secondary drying, will be analyzed, with emphasis on how control of the freezing step can be beneficial and interact with the optimization of the whole process.

Innovations in freeze-drying control and in-line optimization / Barresi, A. A.; Pisano, R.; Fissore, D. - In: Freeze-Drying of Pharmaceutical Products / Fissore D., Pisano R., Barresi A. A., editors. - STAMPA. - Boca Raton (Florida), USA : CRC Press, 2019. - ISBN 978-0367076801. - pp. 99-130 [10.1201/9780429022074-6]

Innovations in freeze-drying control and in-line optimization

Barresi A. A.;Pisano R.;Fissore D.
2019

Abstract

Chapter 6 discusses open- and closed-loop control systems applied to freeze-drying processes, evidencing the possibility of model-based approaches for rejection of disturbances, failure prevention, and process optimization. At the end it will be shown how some of the recently developed tools can be useful for automatic cycle development. All three steps of the process, namely freezing, primary drying, and secondary drying, will be analyzed, with emphasis on how control of the freezing step can be beneficial and interact with the optimization of the whole process.
2019
978-0367076801
9780429022074
Freeze-Drying of Pharmaceutical Products
File in questo prodotto:
File Dimensione Formato  
2019_CRC_FDPP_chap_6-cover&preface.pdf

non disponibili

Descrizione: post print editoriale, con copertina, prefazione e indice
Tipologia: 2a Post-print versione editoriale / Version of Record
Licenza: Non Pubblico - Accesso privato/ristretto
Dimensione 3.01 MB
Formato Adobe PDF
3.01 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/2742701