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EnglishTissue engineering (TE) strategies are aimed at the restoration of tissue architecture and functions by the use of cells in combination with supportive scaffolds. The scaffold should act as a temporary matrix for cell proliferation and extracellular matrix deposition, with subsequent tissue ingrowth. Biomaterials play a critical role in the design of scaffolds and, hence, in the realization of a new functional tissue. A variety of synthetic biomaterials have proved to be useful in the reconstruction of tissues, such as bone, cartilage, and nerve, and some of these are currently used in clinical practice. In this chapter, an overview of the different types of synthetic polymers and their properties and TE applications is reported. They can be nonbiodegradable and biodegradable, and able to produce hydrogel matrices. Special attention has been given to addressing polyurethanes that are available as bioresorbable or biostable biomaterials as well as hydrogels.
| Titolo: | Synthetic biomaterial for regenerative medicine applications |
| Autori: | |
| Data di pubblicazione: | 2017 |
| Titolo del libro: | Kidney Transplantation, Bioengineering and Regeneration, First Edition |
| Abstract: | Tissue engineering (TE) strategies are aimed at the restoration of tissue architecture and functi...ons by the use of cells in combination with supportive scaffolds. The scaffold should act as a temporary matrix for cell proliferation and extracellular matrix deposition, with subsequent tissue ingrowth. Biomaterials play a critical role in the design of scaffolds and, hence, in the realization of a new functional tissue. A variety of synthetic biomaterials have proved to be useful in the reconstruction of tissues, such as bone, cartilage, and nerve, and some of these are currently used in clinical practice. In this chapter, an overview of the different types of synthetic polymers and their properties and TE applications is reported. They can be nonbiodegradable and biodegradable, and able to produce hydrogel matrices. Special attention has been given to addressing polyurethanes that are available as bioresorbable or biostable biomaterials as well as hydrogels. |
| ISBN: | 9780128017340 9780128018361 |
| Appare nelle tipologie: | 2.1 Contributo in volume (Capitolo o Saggio) |
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http://hdl.handle.net/11583/2684105
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