Archivio Istituzionale della RicercaThe pathway that leads toward a successful cycle scale up involves the understanding and control of all three process steps: freezing, primary and secondary drying. This entry addresses each of these steps separately, and also discusses the problem of scaling up a freeze-drying cycle from lab-scale equipment to a production unit. To conclude, the entry reviews current tools available to assist freeze-drying practitioners.
Freeze Drying: Scale-Up Considerations / Barresi, Antonello; Pisano, Roberto - In: Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition / Swarbrick J.. - STAMPA. - New York : CRC Press (Taylor and Francis Group), 2013. - ISBN 1841848190. - pp. 1738-1752 [10.1081/E-EPT4-120050279]
Freeze Drying: Scale-Up Considerations
BARRESI, Antonello;PISANO, ROBERTO
2013
Abstract
The pathway that leads toward a successful cycle scale up involves the understanding and control of all three process steps: freezing, primary and secondary drying. This entry addresses each of these steps separately, and also discusses the problem of scaling up a freeze-drying cycle from lab-scale equipment to a production unit. To conclude, the entry reviews current tools available to assist freeze-drying practitioners.
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https://hdl.handle.net/11583/2513785
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