Archivio Istituzionale della RicercaARSICCIO, ANDREA
Insights from molecular dynamics simulations for the design of lyophilized protein formulations
2024 Arsiccio, Andrea; Pisano, Roberto
Mechanistic Investigation of tert-Butanol’s Impact on Biopharmaceutical Formulations: When Experiments Meet Molecular Dynamics
2023 Rospiccio, Marcello; Casucci, Paola; Arsiccio, Andrea; Udrescu, Claudia; Pisano, Roberto
Thermodynamic modeling and experimental data reveal that sugars stabilize proteins according to an excluded volume mechanism
2023 Arsiccio, Andrea; Sarter, Tim; Polidori, Ilaria; Winter, Gerhard; Pisano, Roberto; Shea, Joan-Emma
A new transfer free energy based implicit solvation model for the description of disordered and folded proteins
2022 Arsiccio, Andrea; Pisano, Roberto; Shea, Joan-Emma
A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII
2022 Arsiccio, Andrea; Metcalfe, Clive; Pisano, Roberto; Raut, Sanj; Coxon, Carmen
Effect of diffusion kinetics on the ice nucleation temperature distribution
2022 Stratta, Lorenzo; Arsiccio, Andrea; Pisano, Roberto
Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins
2021 Arsiccio, Andrea; Rospiccio, Marcello; Shea, Joan-Emma; Pisano, Roberto
Surface treatment of glass vials for lyophilization: Implications for vacuum-induced surface freezing
2021 Regis, F.; Arsiccio, A.; Bourles, E.; Scutella, B.; Pisano, R.
The role of cyclodextrins against interface-induced denaturation in pharmaceutical formulations: a molecular dynamics approach
2021 Rospiccio, M.; Arsiccio, A.; Winter, G.; Pisano, R.
A model-based approach for the rational design of the freeze-thawing of a protein-based formulation
2020 Arsiccio, A.; Marenco, L.; Pisano, R.
ADD force field for sugars and polyols: predicting the additivity of protein-osmolyte interaction
2020 Arsiccio, A.; Ganguly, P.; La Cortiglia, L.; Shea, J. -E.; Pisano, R.
Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach
2020 Arsiccio, A.; Giorsello, P.; Marenco, L.; Pisano, R.
Freeze Drying of Therapeutic Proteins: A Simulation Approach to Optimize Formulation and Process Conditions
2020 Arsiccio, Andrea
Heightened cold-denaturation of proteins at the ice-water interface
2020 Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.
Impact of controlled vacuum induced surface freezing on the freeze drying of human plasma
2020 Arsiccio, A.; Matejtschuk, P.; Ezeajughi, E.; Riches-Duit, A.; Bullen, A.; Malik, K.; Raut, S.; Pisano, R.
The ice-water interface and protein stability: a review
2020 Arsiccio, A.; Pisano, R.
Vacuum-induced surface freezing for the freeze-drying of the Human Growth Hormone: how does nucleation control affect protein stability?
2020 Oddone, I.; Arsiccio, A.; Duru, C.; Malik, K.; Ferguson, J.; Pisano, R.; Matejtschuk, P.
A design space approach for the freezing step of freeze-drying: considerations for process performance and protein stability
2019 Arsiccio, Andrea; Pisano, Roberto
A proximity-based in silico approach to identify redox-labile disulfide bonds: the example of FVIII
2019 Arsiccio, A.; Metcalfe, C.; Riches, A.; Pisano, R.; Raut, S.; Coxon, C.
Achieving continuous manufacturing in lyophilization: technologies and approaches
2019 Pisano, R.; Arsiccio, A.; Capozzi, L. C.; Trout, B. L.
| Citazione | Data di pubblicazione | Autori | File |
|---|---|---|---|
| Insights from molecular dynamics simulations for the design of lyophilized protein formulations / Arsiccio, Andrea; Pisano, Roberto - In: From Current to Future Trends in Pharmaceutical Technology / Pippa N., Demetzos C., Chountoulesi M.. - STAMPA. - Cambridge, Massachusetts : Academic Press, 2024. - ISBN 9780323911115. - pp. 145-175 [10.1016/B978-0-323-91111-5.00004-4] | 1-gen-2024 | Arsiccio, AndreaPisano, Roberto | b-2024_Academic-press_formulation_145-175.pdf |
| Mechanistic Investigation of tert-Butanol’s Impact on Biopharmaceutical Formulations: When Experiments Meet Molecular Dynamics / Rospiccio, Marcello; Casucci, Paola; Arsiccio, Andrea; Udrescu, Claudia; Pisano, Roberto. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8392. - ELETTRONICO. - 20:8(2023), pp. 3975-3986. [10.1021/acs.molpharmaceut.3c00125] | 1-gen-2023 | Marcello RospiccioPaola CasucciAndrea ArsiccioClaudia UdrescuRoberto Pisano | acs.molpharmaceut.3c00125.pdf; mp3c00125_si_001.pdf |
| Thermodynamic modeling and experimental data reveal that sugars stabilize proteins according to an excluded volume mechanism / Arsiccio, Andrea; Sarter, Tim; Polidori, Ilaria; Winter, Gerhard; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 1520-5126. - 145:30(2023), pp. 16678-16690. [10.1021/jacs.3c04293] | 1-gen-2023 | Andrea ArsiccioRoberto Pisano + | a-2023_JACS_145(30)_16678-16690.pdf; a-2023_JACS_145(30)_16678-16690_(pre-print).pdf |
| A new transfer free energy based implicit solvation model for the description of disordered and folded proteins / Arsiccio, Andrea; Pisano, Roberto; Shea, Joan-Emma. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - 126:33(2022), pp. 6180-6190. [10.1021/acs.jpcb.2c03980] | 1-gen-2022 | Arsiccio, AndreaPisano, Roberto + | a-2022_JPCB_126_6180-6190.pdf |
| A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII / Arsiccio, Andrea; Metcalfe, Clive; Pisano, Roberto; Raut, Sanj; Coxon, Carmen. - In: PLOS ONE. - ISSN 1932-6203. - 17:2(2022), pp. 1-24. [10.1371/journal.pone.0262409] | 1-gen-2022 | Arsiccio, AndreaPisano, Roberto + | a-2022_PO_17(2)_e0262409.pdf |
| Effect of diffusion kinetics on the ice nucleation temperature distribution / Stratta, Lorenzo; Arsiccio, Andrea; Pisano, Roberto. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 12:(2022), pp. 1-10. [10.1038/s41598-022-20797-1] | 1-gen-2022 | Stratta, LorenzoArsiccio, AndreaPisano, Roberto | a-2022_SR_12_16334.pdf |
| Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins / Arsiccio, Andrea; Rospiccio, Marcello; Shea, Joan-Emma; Pisano, Roberto. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 125:27(2021), pp. 7397-7405. [10.1021/acs.jpcb.1c04033] | 1-gen-2021 | Arsiccio, AndreaRospiccio, MarcelloPisano, Roberto + | acs.jpcb.1c04033.pdf |
| Surface treatment of glass vials for lyophilization: Implications for vacuum-induced surface freezing / Regis, F.; Arsiccio, A.; Bourles, E.; Scutella, B.; Pisano, R.. - In: PHARMACEUTICS. - ISSN 1999-4923. - ELETTRONICO. - 13:11(2021), p. 1766. [10.3390/pharmaceutics13111766] | 1-gen-2021 | Regis F.Arsiccio A.Pisano R. + | pharmaceutics-13-01766.pdf |
| The role of cyclodextrins against interface-induced denaturation in pharmaceutical formulations: a molecular dynamics approach / Rospiccio, M.; Arsiccio, A.; Winter, G.; Pisano, R.. - In: MOLECULAR PHARMACEUTICS. - ISSN 1543-8384. - STAMPA. - 18:6(2021), pp. 2322-2333. [10.1021/acs.molpharmaceut.1c00135] | 1-gen-2021 | Rospiccio M.Arsiccio A.Pisano R. + | a-2021_MP_18(1)_2322-2333.pdf; a-2021_MP_18(1)_2322-2333_(AAM).pdf |
| A model-based approach for the rational design of the freeze-thawing of a protein-based formulation / Arsiccio, A.; Marenco, L.; Pisano, R.. - In: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. - ISSN 1083-7450. - STAMPA. - 25:7(2020), pp. 823-831. [10.1080/10837450.2020.1743719] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_PDT_25(7)_823-831_(post-print).pdf; a-2020_PDT_25(7)_823-831.pdf |
| ADD force field for sugars and polyols: predicting the additivity of protein-osmolyte interaction / Arsiccio, A.; Ganguly, P.; La Cortiglia, L.; Shea, J. -E.; Pisano, R.. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 124:36(2020), pp. 7779-7790. [10.1021/acs.jpcb.0c05345] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_JPCB_124(36)_7779-7790_(post-print).pdf; a-2020_JPCB_124(36)_7779-7790.pdf |
| Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach / Arsiccio, A.; Giorsello, P.; Marenco, L.; Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 464-475. [10.1016/j.xphs.2019.10.022] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_109(1)_464-475.pdf; a-2020_109(1)_464-475_(post-print).pdf |
| Freeze Drying of Therapeutic Proteins: A Simulation Approach to Optimize Formulation and Process Conditions / Arsiccio, Andrea. - (2020 Feb 13), pp. 1-286. | 13-feb-2020 | ARSICCIO, ANDREA | thesis-pdfA.pdf; Summary.pdf |
| Heightened cold-denaturation of proteins at the ice-water interface / Arsiccio, A.; Mccarty, J.; Pisano, R.; Shea, J. -E.. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - 142:12(2020), pp. 5722-5730. [10.1021/jacs.9b13454] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_JACS_142(12)_5722-5730.pdf |
| Impact of controlled vacuum induced surface freezing on the freeze drying of human plasma / Arsiccio, A.; Matejtschuk, P.; Ezeajughi, E.; Riches-Duit, A.; Bullen, A.; Malik, K.; Raut, S.; Pisano, R.. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - STAMPA. - 582:(2020), p. 119290. [10.1016/j.ijpharm.2020.119290] | 1-gen-2020 | Arsiccio A.Pisano R. + | a-2020_IJP_582_119290_(post-print).pdf; a-2020_IJP_582_119290.pdf |
| The ice-water interface and protein stability: a review / Arsiccio, A.; Pisano, R.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:7(2020), pp. 2116-2130. [10.1016/j.xphs.2020.03.022] | 1-gen-2020 | Arsiccio A.Pisano R. | a-2020_JPS_109(7)_2116-2130_(post-print).pdf; a-2020_JPS_109(7)_2116-2130.pdf |
| Vacuum-induced surface freezing for the freeze-drying of the Human Growth Hormone: how does nucleation control affect protein stability? / Oddone, I.; Arsiccio, A.; Duru, C.; Malik, K.; Ferguson, J.; Pisano, R.; Matejtschuk, P.. - In: JOURNAL OF PHARMACEUTICAL SCIENCES. - ISSN 0022-3549. - STAMPA. - 109:1(2020), pp. 254-263. [10.1016/j.xphs.2019.04.014] | 1-gen-2020 | Oddone I.Arsiccio A.Pisano R. + | a-2020_JPS_109(1)_254-263.pdf |
| A design space approach for the freezing step of freeze-drying: considerations for process performance and protein stability / Arsiccio, Andrea; Pisano, Roberto. - STAMPA. - (2019). (Intervento presentato al convegno 7th European Conference “EuroDrying’2019” tenutosi a Torino nel July 10-12, 2019). | 1-gen-2019 | Andrea ArsiccioRoberto Pisano | 48_ED2019_arsiccio_DS.pdf |
| A proximity-based in silico approach to identify redox-labile disulfide bonds: the example of FVIII / Arsiccio, A.; Metcalfe, C.; Riches, A.; Pisano, R.; Raut, S.; Coxon, C.. - ELETTRONICO. - (2019). (Intervento presentato al convegno ISTH 2019 Congress tenutosi a Melbourne, Australia nel July 6-10). | 1-gen-2019 | Arsiccio A.Pisano R. + | - |
| Achieving continuous manufacturing in lyophilization: technologies and approaches / Pisano, R.; Arsiccio, A.; Capozzi, L. C.; Trout, B. L.. - In: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. - ISSN 0939-6411. - STAMPA. - 142:(2019), pp. 265-279. [10.1016/j.ejpb.2019.06.027] | 1-gen-2019 | Pisano R.Arsiccio A.Capozzi L. C. + | a-2019_EJPB_142(1)_265-279.pdf |